Publications by authors named "Julia K Deanehan"
Article Synopsis
- The study investigates the effectiveness of procalcitonin as a diagnostic tool for childhood bacterial pneumonia, which is a significant health concern.
- It analyzed data from 25 studies involving nearly 2,900 patients, finding that procalcitonin showed moderate sensitivity (64%) and specificity (72%) for diagnosing bacterial pneumonia.
- The authors suggest using procalcitonin alongside other diagnostic methods, as it isn't strong enough to be relied on alone, particularly since elevated levels did not significantly correlate with bacterial pneumonia cases.
Article Synopsis
- Ultrasound is nearly as accurate as standard X-rays for diagnosing upper extremity fractures in children, showing high sensitivity and specificity rates of 0.95 each.
- A review of 32 studies indicated that while ultrasound is reliable overall, it may perform differently based on fracture location, particularly for elbow fractures.
- The findings support the use of ultrasound as an alternative diagnostic tool for pediatric fractures, particularly for those outside of the elbow region.
Objectives: A multidisciplinary pediatric difficult airway team was created at our institution to respond to hospital-wide airway emergencies. We report the characteristics, indications, and outcomes of these activations that occur in the pediatric emergency department (PED).
Methods: Retrospective, single-center cohort study comprised all difficult airway team activations occurring in the PED from the program's inception in 2008 to 2018.
Article Synopsis
- Lung ultrasound (LUS) is emerging as an effective diagnostic tool for childhood pneumonia, offering high sensitivity (94%) and specificity (92%) compared to traditional chest x-rays.
- A systematic review and meta-analysis of 25 studies involving over 3,350 participants indicated that sonographer experience significantly impacts the diagnostic accuracy of LUS, with advanced sonographers performing better than novices.
- The study utilized rigorous methods, including QUADAS-2 for quality assessment and random-effect models for evaluating performance metrics, highlighting the potential of LUS as a reliable alternative in diagnosing pneumonia in children.
Objective: It is unclear whether point-of-care ultrasound (POCUS) by emergency medicine physicians is as accurate as radiology-performed ultrasound (RADUS). We aim to summarize the diagnostic accuracy of ultrasonography for intussusception and to compare the performance between POCUS and RADUS.
Methods: Databases were searched from inception through February 2018 using pre-defined index terms.
Point-of-Care Ultrasound Identification of a Psoas Abscess in a Child Presenting With Hip Pain.
Pediatr Emerg Care
June 2017
This case-report describes a 4-year-old girl brought to the emergency department for the evaluation of limp and elevated inflammatory markers. The patient's history and physical examination did not reveal a clear source of pathology. Point-of-care ultrasound identified a right-sided psoas abscess that was confirmed with computed tomography scan.
View Article and Find Full Text PDFBackground: Although Lyme and septic arthritis of the knee may have similar clinical presentations, septic arthritis requires prompt identification and treatment to avoid joint destruction. We sought to determine whether synovial fluid cell counts alone can discriminate between Lyme, septic, and other inflammatory arthritis.
Methods: We conducted a retrospective cohort study of children aged 1 to 18 years with knee monoarthritis who presented to 1 of 2 pediatric emergency departments located in Lyme endemic areas.
Objective: Because Lyme and septic arthritis may present similarly, we sought to identify children with knee monoarthritis at low risk for septic arthritis who may not require arthrocentesis.
Methods: We performed a retrospective study of children with knee monoarthritis presenting to 1 of 2 pediatric centers, both located in Lyme disease-endemic areas. Septic arthritis was defined by a positive result on synovial fluid culture or synovial fluid pleocytosis with a positive blood culture result.
The activity of the kinase Aurora-A (Aur-A) peaks during mitosis and depends on phosphorylation by one or more unknown kinases. Mitotic phosphorylation sites were mapped by mass spec sequencing of recombinant Aur-A protein that had been activated by incubation in extracts of metaphase-arrested Xenopus eggs. Three sites were identified: serine 53 (Ser-53), threonine 295 (Thr-295), and serine 349 (Ser-349), which are equivalent to Ser-51, Thr-288, and Ser-342, respectively, in human Aur-A.
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