Korean version of the convalescence and recovery evaluation: translation and linguistic validation.

Background: To develop a Korean version of the original English version of the convalescence and recovery evaluation (CARE) questionnaire. The linguistic validation of the CARE questionnaire was tested on Korean patients who underwent abdominal and pelvic surgery.

Methods: The CARE questionnaire was translated and validated linguistically in the following steps.

Examination of clinically-derived p210 BCR/ABL1 RhoGEF mutations in a murine bone marrow transplantation model of CML.

Expression of the p210 BCR/ABL1 fusion protein has been described in virtually all patients with chronic myelogenous leukemia (CML). Previous studies have identified a guanine nucleotide exchange factor (RhoGEF) domain within BCR that is retained in p210 BCR/ABL1. Missense mutations at residues T654 (T654K) and F547 (F547L) within this domain have been reported in a CML patient in blast crisis (BC).

Korean version of the G-8 geriatric screening tool: Translation and linguistic validation.

Objective: To develop a Korean version of the G-8 questionnaire validated with Korean patients over 70 years-of-age who were scheduled to undergo cancer surgery.

Materials And Methods: We conducted a translation study over a nine-month period from February to November 2017. Permission was received to use the original version of the G-8 questionnaire for forward translation into Korean and reconciliation, for backward translation of the translated Korean version into English, for cognitive debriefing, and final proofreading.

Colonoscopy utilization in rural areas by general surgeons: An analysis of the National Ambulatory Medical Care Survey.

Background: One in three adults above 50 years old have not been screened for colorectal cancer as of 2013. Rural areas have even lower screening and have more general surgeons compared to gastroenterologists, offering surgeons as a reservoir for necessary services.

Methods: Public data from the 2006-2015 CDC National Ambulatory Medical Care Survey was analyzed using SAS.

Cellular Response to Exponentially Increasing and Decreasing Dose Rates: Implications for Treatment Planning in Targeted Radionuclide Therapy.

The treatment of cancer using targeted radionuclide therapy is of interest to nuclear medicine and radiation oncology because of its potential for killing tumor cells while minimizing dose-limiting toxicities to normal tissue. The ionizing radiations emitted by radiopharmaceuticals deliver radiation absorbed doses over protracted periods of time with continuously varying dose rates. As targeted radionuclide therapy becomes a more prominent part of cancer therapy, accurate models for estimating the biologically effective dose (BED) or equieffective dose (EQD2) will become essential for treatment planning.