Publications by authors named "Julia Gonzalez Gonzalez"

Article Synopsis
  • Self-care and empowerment in heart failure (HF) patients are crucial for better health outcomes, but there is limited information on their understanding of the condition and satisfaction with care.
  • A study involving 281 patients from 14 heart failure units revealed that patients had a good grasp of their condition, with an average knowledge score of 80.7%, although some gaps remain.
  • Despite these knowledge gaps, the majority of participants expressed high satisfaction with their care, with 98.2% likely to recommend the heart failure units to others.
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Melatonin, an endogenously produced hormone, might potentially limit the ischemia reperfusion injury and improve the efficacy of mechanical reperfusion with primary percutaneous coronary intervention (pPCI) in ST-segment elevation myocardial infarction (STEMI). This study was aimed to evaluate whether the treatment effect of melatonin therapy in patients with STEMI is influenced by the time to administration. We performed a post hoc analysis of the Melatonin Adjunct in the Acute Myocardial Infarction Treated With Angioplasty trial (NCT00640094), which randomized STEMI patients to melatonin (intravenous and intracoronary bolus) or placebo during pPCI.

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The MARIA randomized trial evaluated the efficacy and safety of melatonin for the reduction of reperfusion injury in patients undergoing revascularization for ST-elevation myocardial infarction (STEMI). This was a prespecified interim analysis. A total of 146 patients presenting with STEMI within 6 hours of chest pain onset were randomized to receive intravenous and intracoronary melatonin (n=73) or placebo (n=73) during primary percutaneous coronary intervention (PPCI).

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