Effects of intensity of treadmill training on developmental outcomes and stepping in infants with Down syndrome: a randomized trial.

Background And Purpose: Infants with Down syndrome (DS) are consistently late walkers. The purpose of this investigation was to test the effects of individualized, progressively more intense treadmill training on developmental outcomes in infants with DS.

Subjects: Thirty infants born with DS were randomly assigned to receive lower-intensity, generalized treadmill training or higher-intensity, individualized training implemented by their parents in their homes.