Publications by authors named "Julia Denissen"

Antibiotic resistance and virulence profiles of , , and , isolated from water sources collected in informal settlements, were compared to clinical counterparts. Cluster analysis using repetitive extragenic palindromic sequence-based polymerase chain reaction (REP-PCR) indicated that, for each respective species, low genetic relatedness was observed between most of the clinical and environmental isolates, with only one clinical (PAO1) and one clinical (P2) exhibiting high genetic similarity to the environmental strains. Based on the antibiograms, the clinical Ef CD1 was extensively drug resistant (XDR); all isolates ( = 12) (except ATCC 13883) were multidrug resistant (MDR), while the ( = 16) isolates exhibited higher susceptibility profiles.

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The ESKAPE (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter spp.) pathogens are characterised by increased levels of resistance towards multiple classes of first line and last-resort antibiotics. Although these pathogens are frequently isolated from clinical environments and are implicated in a variety of life-threatening, hospital-associated infections; antibiotic resistant ESKAPE strains have been isolated from environmental reservoirs such as surface water, wastewater, food, and soil.

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