Publications by authors named "Julia C Carmona-Bozo"
Article Synopsis
- This study investigates the link between hypoxia and vascular function in estrogen receptor-positive breast cancer using advanced imaging techniques and immunohistochemical markers.
- The research involved treatment-naive women who underwent [F]-FMISO-PET/MRI, measuring variables like vessel diameter and microvessel density to assess hypoxia.
- Results showed a negative correlation between hypoxia and vascular metrics, indicating that lower blood vessel density and smaller vessel sizes are linked to increased hypoxia in breast tumors.
Objectives: Hypoxia is associated with poor prognosis and treatment resistance in breast cancer. However, the temporally variant nature of hypoxia can complicate interpretation of imaging findings. We explored the relationship between hypoxia and vascular function in breast tumours through combined F-fluoromisonidazole ( F-FMISO) PET/MRI, with simultaneous assessment circumventing the effect of temporal variation in hypoxia and perfusion.
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