Synergistic antimicrobial activities of epigallocatechin gallate, myricetin, daidzein, gallic acid, epicatechin, 3-hydroxy-6-methoxyflavone and genistein combined with antibiotics against ESKAPE pathogens.

Aim: To verify synergistic effects, we investigated the antimicrobial activity of seven phenolic phytochemicals (gallic acid; epicatechin; epigallocatechin gallate; daidzein; genistein; myricetin; 3-hydroxy-6-methoxyflavone) in combination with six antibiotics against multidrug-resistant isolates from the ESKAPE group.

Methods And Results: To investigate single phytochemicals and combinations, initial microdilution and checkerboard assays were used, followed by time-kill assays to evaluate the obtained results. The research revealed that phenolic compounds on their own resulted in little or no inhibitory effects.

Factors Contributing to Violence Against Children: Insights From a Multi-informant Study Among Family-Triads From Three East-African Refugee Camps.

Parental violence poses a considerable, yet mitigable risk for the mental health and well-being of refugee children living in resource-poor refugee camps. However, little is known about potential risk factors for parental violence in these settings. Using an ecological systems perspective and a multi-informant approach, we investigated ontogenic (parental childhood experiences of violence), microsystem (parents' and children's psychopathology) and exosystem (families' monthly household income) risk factors for child-directed parental violence in a sample of 226 Burundian families living in refugee camps in Tanzania.

Universal behavior of coupled order parameters below three dimensions.

We explore universal critical behavior in models with two competing order parameters, and an O(N) ⊕O(M) symmetry for dimensions d≤3. In d=3, there is always exactly one stable renormalization group fixed point, corresponding to bicritical or tetracritical behavior. Employing pseudospectral techniques to solve functional renormalization group equations in a two-dimensional field space, we uncover a more intricate structure of fixed points in d<3, where two additional bicritical fixed points play a role.

Measuring the spatial polarization distribution of multimode beams emerging from passive step-index large-mode-area fibers.

We measure the polarization state of each guided transversal mode propagating in step-index large-mode-area fibers (V≈4) using a correlation-filter based measurement technique in combination with a Stokes parameter measurement. The entire emerging beam, expressed in terms of a phase-dependent superposition of linearly polarized modes, demonstrates spatially varying polarization properties. By knowing the information about modal amplitudes and phase differences, full information about the optical field is available.