Background: Patients are commonly reported as being allergic to beta-lactam (BL) antibiotics. However, many patients with this reported allergy are able to receive BL treatments because they do not have true allergies. In many cases these are simply intolerances due to side effects reported as an allergy.
View Article and Find Full Text PDFBacterial endophthalmitis constitutes a medical emergency due to the possibility of leading to blindness unless treatment is administered quickly. The usual treatment seeks to cover both gram-positive and gram-negative bacteria by intravitreal injections of vancomycin and ceftazidime. In the present work, we sought to determine the physicochemical and microbiological stability of intravitreal syringes of vancomycin 10 mg/mL in order to be able to store them as long as possible to have immediate stock.
View Article and Find Full Text PDFObjectives: This study aimed to describe the actions taken to implement a telepharmacy programme with home medication dispensing and informed delivery in an outpatient pharmaceutical care unit of a tertiary hospital, where approximately 5000 patients are treated per year. It also aimed to substantiate the applicability and benefits of the programme through analysing the findings and measuring patient satisfaction.
Methods: We identified the operational, logistical, technological and legal needs, as well as the need for training, information and coordination with the care team and patient associations.
Background: We investigated physical and chemical stability of daptomycin and vancomycin in heparin or sodium citrate lock solutions. The aim of this study was to find the optimal combination of antimicrobials and additives for lock solutions, which maximized patient safety.
Methods: Vancomycin and daptomycin were diluted with heparin or sodium citrate to achieve final concentrations of vancomycin-heparin 2.