Publications by authors named "Julia Bak"
Grading and histologic typing of endometrial cancer in biopsy material has a direct impact on the decision to perform lymphadenectomy and/or omentectomy in many cancer centers. Endometrial biopsies are among the most common general surgical pathology specimens. Multiple studies have shown that biopsy diagnosis suffers from a lack of reproducibility.
View Article and Find Full Text PDFAims: To assess the variation in ovarian carcinoma type diagnosis among gynaecological pathologists from Nordic countries, and whether a rationally designed panel of immunohistochemical markers could improve diagnostic reproducibility.
Methods And Results: Eight pathologists from four countries (Sweden, Denmark, Norway, and Finland) received an educational lecture on the diagnosis of ovarian carcinoma type. All tumour-containing slides from 54 ovarian carcinoma cases were independently reviewed by the participants, who: (i) determined type purely on the basis of histology; (ii) indicated whether they would apply immunohistochemistry in their routine practice; and (iii) determined type after reviewing the staining results.
Article Synopsis
- The study evaluated the disease-specific mortality of conservatively managed incidental prostate cancer (T1a and T1b) and explored various prognostic factors.
- Since 1987, data from patients treated in Sweden were analyzed, focusing on factors such as tumor size and Gleason score from a sample of 197 patients who underwent surgery.
- Findings revealed that 20% of patients died from prostate cancer over an average follow-up of 7.8 years, with significant predictors of mortality being T1b classification, Gleason score above 5, and high levels of Ki-67.