Publications by authors named "Julia Ariana de S Gomes"
Article Synopsis
- Oxidative imbalance, changes in BDNF levels, and mitochondrial issues are linked to bipolar disorder and its related health problems, like heart disease.
- Carvedilol (CVD), a beta-blocker used for hypertension, has antioxidant and mitochondrial benefits, leading researchers to explore its potential in mitigating mania-like symptoms triggered by lisdexamfetamine (LDX) in male Wistar rats.
- The study found that CVD effectively prevented and reversed behavioral and neurochemical changes caused by LDX, and a combination of CVD and another drug enhanced the overall treatment effect, suggesting a possible antimanic role for CVD in bipolar disorder management.
