Where to deploy pre-exposure prophylaxis (PrEP) in sub-Saharan Africa?

Objective: Two randomised controlled trials showed that pre-exposure prophylaxis (PrEP) reduces HIV transmission between heterosexual men and women. We model the potential impact on transmission and cost-effectiveness of providing PrEP in sub-Saharan Africa.

Methods: We use a deterministic, compartmental model of HIV transmission to evaluate the potential of a 5-year PrEP intervention targeting the adult population of 42 sub-Saharan African countries.

Acculturation and its association with health-risk behaviors in a rural Latina population.

Purpose: To evaluate the performance of proxy measures of acculturation and to examine the association between acculturation and selected health-risk behaviors.

Methods: Participants were 1062 Latina pregnant women who received prenatal care at clinics in San Joaquin County, California between 1999 and 2001. We used the receiver-operating characteristic (ROC) curve to characterize the sensitivity and specificity of proxy measures and regression analysis to examine health-risk behaviors.