Human blood barrier models: architectures and applications.

Blood barriers serve as key points of transport for essential molecules as well as lines of defense to protect against toxins. modeling of these barriers is common practice in the study of their physiology and related diseases. This review describes a common method of using an adaptable, low cost, semipermeable, suspended membrane to experimentally model three blood barriers in the human body: the blood-brain barrier (BBB), the gut-blood barrier (GBB), and the air-blood barrier (ABB).