Publications by authors named "Julia A Brettschneider"
Background: Telemonitoring of circadian and sleep cycles could identify shift workers at increased risk of poor health, including cancer and cardiovascular diseases, thus supporting personalized prevention.
Methods: The Circadiem cross-sectional study aimed at determining early warning signals of risk of health alteration in hospital nightshifters (NS) versus dayshifters (DS, alternating morning and afternoon shifts). Circadian rhythmicity in activity, sleep, and temperature was telemonitored on work and free days for one week.
Article Synopsis
- Serial block face scanning electron microscopy (SBF-SEM) enables detailed 3D analysis of cells, particularly useful for studying microtubules in the mitotic spindle of human cells.
- The study highlights a new workflow that combines light microscopy with SBF-SEM to achieve improved visualization of microtubules, bridging fibers, and cellular membranes during mitosis.
- The research also introduces computational tools that analyze the spatial arrangement of microtubules and shows their sensitivity to TACC3 levels affecting microtubule order in mitotic spindles.