Publications by authors named "Jules Stern"
Article Synopsis
- Immunocompromised patients receiving venoarterial extracorporeal membrane oxygenation (VA-ECMO) exhibit high mortality rates, with 70% dying within 90 days and 75% within a year.
- Factors contributing to these outcomes include older age and elevated pre-ECMO lactate levels, indicating higher risk.
- The study highlights severe complications such as hemorrhages and infections, with immunocompromised individuals having twice the risk of 90-day mortality compared to non-immunocompromised patients.
Article Synopsis
- Upper gastrointestinal bleeding (UGIB) is a frequent issue in adults undergoing VA-ECMO for severe heart problems, with the study aiming to identify its risk factors and outcomes.
- In a study of 455 patients, 10% experienced UGIB, with a significantly higher mortality rate and longer hospital stays compared to those without UGIB.
- Key risk factors for UGIB included a history of peptic ulcers, use of dual antiplatelet therapy, and undergoing extracorporeal cardiopulmonary resuscitation.
Background: The outcomes of lung transplantation (LT) recipients who received a graft from a brain-dead donor after successful resuscitation from cardiac arrest (CA donors) have been poorly described. This study compared the one-year survival of LT recipients depending on the CA status of the donor.
Methods: This prospective observational single-centre study analysed all consecutive patients who underwent LT at Bichat Claude Bernard Hospital, Paris, between January 2016 and December 2020.
Article Synopsis
- * A study in an ICU involving 219 septic patients showed that 15% had sepsis-associated liver dysfunction, which was associated with lower HDL levels.
- * Despite the lower HDL-C concentrations in patients with liver dysfunction, no overall relationship was found between lipoprotein levels and liver dysfunction markers affecting outcomes.
Background: High-density lipoproteins (HDLs), particles characterized by their reverse cholesterol transport function, display pleiotropic properties, including anti-inflammatory and antioxidant functions. Moreover, all lipoproteins (HDLs but also low-density lipoproteins (LDLs)) neutralize lipopolysaccharides, leading to increased bacterial clearance. These two lipoproteins decrease during sepsis, and an association between low lipoprotein levels and poor outcome was reported.
View Article and Find Full Text PDFPurpose: The pressure recording analytical method (PRAM) monitor is a non-invasive pulse contour cardiac output (CO) device that cannot be considered interchangeable with the gold standard for CO estimation. It, however, generates additional hemodynamic indices that need to be evaluated. Our objective was to investigate the performance of a multiparametric predictive score based on a combination of several parameters generated by the PRAM monitor to predict fluid responsiveness.
View Article and Find Full Text PDFBackground: The ability of the pressure recording analytical method (PRAM) in tracking change in cardiac output (ΔCO) after a fluid challenge in ICU needs to be evaluated with the most contemporary comparison methods recommended by experts.
Objective: Our objective was to report the trending ability of PRAM in tracking ΔCO after a fluid challenge in ICU and to compare this with oesophageal Doppler monitoring (ODM).
Design: Prospective, observational study.