Publications by authors named "Jules M Ndoli"
Article Synopsis
- In 2023, updated data from Huye district, Rwanda revealed that 17.5% of malaria patients exhibited markers for artemisinin resistance, nearly doubling from 2019.
- Markers for lumefantrine tolerance, specifically N86, approached a fixation rate of 98%.
- Overall, while resistance markers for both artemisinin and lumefantrine are on the rise, the increase is happening at a relatively slow pace in southern Rwanda.
Plasmodium vivax is the second-most common malaria pathogen globally, but is considered very rare in the predominantly Duffy-negative sub-Saharan African population. In 259 malaria patients from highland southern Rwanda, we assessed Plasmodium species and Duffy blood group status by polymerase chain reaction (PCR). Plasmodium falciparum, P.
View Article and Find Full Text PDFMulti-drug resistant (MDR), gram-negative , such as () limit therapeutic options and increase morbidity, mortality, and treatment costs worldwide. They pose a serious burden on healthcare systems, especially in developing countries like Rwanda. Several studies have shown the effects caused by the global spread of extended-spectrum beta-lactamase (ESBL)-producing .
View Article and Find Full Text PDFMultidrug-resistant gram-negative (MRGN) bacteria are a serious threat to global health. We used genomics to study MRGN obtained from houseflies in a tertiary Rwandan hospital. Our analysis revealed a high abundance of different MRGN including E.
View Article and Find Full Text PDFObjectives: To assess the presence and risk factors of intestinal carriage of extended-spectrum beta-lactamase-producing Enterobacteriaceae (ESBL-PE) among patients admitted to the University Teaching Hospital of Butare and among their attending caregivers, and to analyse the acquisition of ESBL-PE carriage during hospital stay and associated factors.
Methods: We screened 392 patients and their attending caregivers at admission and discharge for ESBL-PE carriage. Bacterial species were determined using the API-20E system, and antimicrobial susceptibility testing was performed by agar disc diffusion.