The Differences Between Sculptra and AestheFill Reconstitution Processes.

Biostimulators have been increasingly popular for facial rejuvenation in recent years. Among them, Sculptra (based on poly-L-lactic acid (PLLA)) and AestheFill (based on poly-D,L-lactic acid (PDLLA)) are supplied as lyophilized powders in vials. Both need to be reconstituted with sterile water into homogeneous suspensions before injection.

Warm Water Soaking Followed by the Back-and-Forth Pushing: An Easy Reconstitution Method for Eliminating Micro-aggregates in AestheFill Suspension.

AestheFill is supplied as lyophilized granules in vials and requires reconstitution with sterile water for injection before use. It has various applications and is often called a versatile biostimulator. It can be used for skin texture improvement through intra-dermal injection using an automatic injector with 32G multi-needles.

A Randomized, Evaluator-Blinded, Multicenter Study to Compare Injectable Poly-D,L-Lactic Acid vs Hyaluronic Acid for Nasolabial Fold Augmentation.

Background: Injectable poly-D,L-lactic acid (PDLLA), under the brand name of AestheFill (REGEN Biotech, Inc., Seoul, South Korea), is a biocompatible, biodegradable, and biostimulatory product utilized to correct soft tissue volume loss. Its efficacy and safety have not been fully studied in a large cohort.

The AestheCode System: A Safe and Efficient Guide for AestheFill Injection.

AestheFill is a biostimulator based on poly-D,L-lactic acid. It is supplied as lyophilized powders and is referred to as a versatile biostimulator. According to the amount of water added, the suspensions can be vary in thickness which can be divided into four groups for different indications: the thickest suspension (D) for nose or chin augmentation, thick suspension (D) for deep wrinkle correction, thin suspension (D) for shallow wrinkle correction, and super-thin suspension (D) for skin rejuvenation.

Retrograde flow phenomenon of poly-D,L-lactic acid filler injection over lower eyelids.

The occurrence of 'retrograde flow along the cannula/needle tract' during filler injections has not been extensively addressed in the existing literature, possibly because it is often imperceptible unless the injection is conducted at a superficial layer. In our experience with poly-D,L-lactic acid filler for lower eyelid injections, we have observed and documented this phenomenon through the skin. This article aims to elucidate and illustrate the retrograde flow phenomenon and discuss the factors influencing it.

miR-328-3p Affects Axial Length Via Multiple Routes and Anti-miR-328-3p Possesses a Potential to Control Myopia Progression.

Purpose: We previously reported miR-328-3p as a novel risk factor for myopia through a genetic association study of the PAX6 gene. In the present study, we first explored the effects of miR-328-3p on other myopia-related genes, and then tested whether anti-miR-328-3p may be used for myopia control.

Methods: The luciferase report assay and transient transfection were used to confirm miR-328-3p target genes.

Nonsurgical lower eyelid rejuvenation using injectable poly-d,l-lactic acid in Asian patients.

Background: Filler injection for lower eyelid rejuvenation remains a difficult subject due to many complicated anatomic changes as the face ages.

Objectives: To propose an alternative, simple, and effective filler injection method in lower eyelids for Asian patients.

Methods: Any patient who has tear trough deformities, infra-orbital hollows, nasojugal grooves, dark eye circles, as well as mild eyebags is a potential candidate for this method.

Reconstitution of Injectable Poly-d,l-lactic Acid: Efficacy of Different Diluents and a New Accelerating Method.

Unlabelled: Injectable poly-d,l-lactic acid (PDLLA) is a new collagen-stimulating filler containing PDLLA microspheres and carboxymethyl cellulose. It is available as a lyophilized powder that must be reconstituted with a diluent before administration. The aims of this study were to investigate the efficacy of different diluents and a new accelerating "back-and-forth" method.

Pelvic retroperitoneal cyst during pregnancy.

Objective: The diagnosis and treatment of adnexal mass during pregnancy is a major challenge for obstetricians. A rare case is reported of retroperitoneal cystic lesion during pregnancy.

Case Report: A 31-year-old woman was diagnosed with an adnexal cystic lesion at 8 weeks of gestation and underwent laparoscopic surgery at 14 weeks of gestation.

Downregulation of the integrin α(v) signaling pathway in uterine leiomyomas.

Objective: To investigate alterations of integrin α(v), survival and apoptosis signaling pathways in uterine leiomyomas.

Materials And Methods: In a prospective study of 50 women with uterine leiomyomas that had been pathologically confirmed, specimens were obtained laparoscopically from 2007 to 2009. The expressions of integrin α(v) signaling pathways (Ras/Raf/ERK1/2, Akt and cleaved caspase-3), surface microstructures by surface electron microscopy and immunohistochemical findings were assessed.

Uterine rupture secondary to placenta percreta in a near-term pregnant woman with a history of hysterotomy.

Uterine rupture during near-term pregnancy is a life-threatening condition. A 31-year-old pregnant woman with a breech presentation at the gestation age of 35(+2) weeks had complained of a dull abdominal pain for days. She was treated 2 years ago with bilateral uterine artery ligation and hysterotomy for removal of the retained placenta.

Uterine artery occlusion and myomectomy for treatment of pregnant women with uterine leiomyomas who are undergoing cesarean section.

Aim: To evaluate the efficacy of uterine artery occlusion and myomectomy (UAO+M) for pregnant women with uterine leiomyomas who are undergoing cesarean section (CS).

Methods: Seventy-two women with uterine leiomyomas undergoing CS for obstetrical reasons were enrolled into this case-control study. Thirty-six patients underwent UAO+M during CS (UAO+M group), and 36 received CS alone (Control group).