Publications by authors named "Jui-En Lo"
Article Synopsis
- Continuous positive airway pressure (CPAP) is primarily prescribed for obstructive sleep apnea (OSA), but many patients still experience respiratory issues or need higher pressures during treatment.
- The study aimed to create predictive models to better forecast CPAP outcomes using both clinical and physiological data, comparing traditional regression methods to more advanced machine learning techniques.
- Results showed that machine learning models, particularly random forest methods that included physiological traits, significantly outperformed traditional regression models in predicting residual apnea-hypopnea index (AHI), highlighting the importance of using diverse data for more accurate predictions in OSA therapy.
Purpose: Pleiotropic cardiovascular benefits of sodium-glucose cotransporter 2 inhibitors (SGLT2i) due to vascular remodeling effects have been demonstrated in patients with type 2 diabetes mellitus. It is unclear whether a similar benefit may be seen for glaucoma. The purpose of this study was to assess the effect of SGLT2i on the risk of glaucoma in patients with type 2 diabetes.
View Article and Find Full Text PDFObjective: Patients with systemic lupus erythematosus (SLE) were excluded from sodium-glucose cotransporter 2 inhibitors (SGLT2i) clinical trials. It is unknown whether the cardiorenal benefits of SGLT2i extend to patients with SLE and comorbid type 2 diabetes (T2D).
Methods: We performed an emulated clinical trial in an insurance-based cohort in the United States, evaluating SGLT2i versus dipeptidyl peptidase-4 inhibitors (DPP4i) for primary prevention of cardiovascular, renal, and other clinical outcomes among patients with both SLE and comorbid T2D.
Artificial intelligence for diagnosing exudative age-related macular degeneration.
Cochrane Database Syst Rev
October 2024
Background: Age-related macular degeneration (AMD) is a retinal disorder characterized by central retinal (macular) damage. Approximately 10% to 20% of non-exudative AMD cases progress to the exudative form, which may result in rapid deterioration of central vision. Individuals with exudative AMD (eAMD) need prompt consultation with retinal specialists to minimize the risk and extent of vision loss.
View Article and Find Full Text PDFAllergic Rhinitis and Keratoconus: A Systematic Review and Meta-Analysis.
J Allergy Clin Immunol Pract
November 2024
Background: The relationship between keratoconus and various allergic diseases has been a subject of controversy.
Objective: In the present study, a systematic review and meta-analysis was conducted to investigate the association between allergic rhinitis (AR) and keratoconus.
Methods: Relevant and eligible studies from PubMed, Web of Science, and the Cochrane Library were systematically reviewed to evaluate the association between AR and keratoconus.
Purpose: To determine the risk and incidence of keratitis following treatment with epidermal growth factor receptor inhibitors (EGFRi) and subtypes of EGFRi-associated keratitis.
Methods: This multi-center cohort study included EGFRi-treated patients and non-users with lung cancer between 2010 and 2023. EGFRi included first-generation agent gefitinib and erlotinib, second-generation agent afatinib, and third-generation agent osimertinib.
Genotypes Influence Clinical Progression in EYS-Associated Retinitis Pigmentosa.
Transl Vis Sci Technol
July 2022
Purpose: The purpose of this study was to investigate the genetic and clinical characteristics of eyes shut homolog (EYS)-associated retinitis pigmentosa (RP).
Methods: This was a retrospective cross-sectional observational study of 36 patients with EYS-associated autosomal recessive RP (arRP).
Results: The gene sequencing results revealed that c.
This study is aimed at evaluating a deep transfer learning-based model for identifying diabetic retinopathy (DR) that was trained using a dataset with high variability and predominant type 2 diabetes (T2D) and comparing model performance with that in patients with type 1 diabetes (T1D). The Kaggle dataset, which is a publicly available dataset, was divided into training and testing Kaggle datasets. In the comparison dataset, we collected retinal fundus images of T1D patients at Chang Gung Memorial Hospital in Taiwan from 2013 to 2020, and the images were divided into training and testing T1D datasets.
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