Publications by authors named "Jui-Chieh Yin"
Article Synopsis
- Sortases are enzymes in Gram-positive bacteria that attach surface proteins to the cell wall, using a specific signal at the protein's C-terminus.
- The study investigates how sortase B (Cd-SrtB) specifically recognizes and binds to the peptide substrate PPKTG, utilizing structural studies and computational modeling.
- Key findings indicate that the fourth amino acid from the cleavage site of PPKTG is crucial for effective recognition and cleavage by sortase B, enhancing our understanding of substrate specificity in these enzymes.