Silent information regulator 2 (Sir2) is a conserved NAD-dependent histone deacetylase crucial for regulating cellular stress response and the aging process in . In this study, we investigated the molecular mechanism underlying how the absence of Sir2 can lead to altered stress susceptibilities in under different environmental and physiological conditions. In a glucose-complex medium, the Δ strain showed increased sensitivity to HO compared to the wild-type strain during the post-diauxic phase.
View Article and Find Full Text PDFPurpose: Visceral fat (VF) is closely associated with many metabolic risk factors and is also known to be a strong predictive factor for severe metabolic complications in adults. But there are only a few studies concerning the association of VF and risk factors for metabolic syndrome (MS) in children and adolescents. In our study, we emphasized the association of VF [measured by VF computed tomography (VFCT)] and risk factors for metabolic syndrome in children and adolescents.
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