Inflamed Tissue-Targeting Polyphenol-Condensed Antioxidant Nanoparticles with Therapeutic Potential.

Inflammation is essential for pathogen eradication and tissue repair; However, chronic inflammation can bring on multi-organ dysfunction due to an overproduction of reactive oxygen species (ROS). Among various anti-inflammatory agents, polyphenol-based nanotherapeutics offer potential advantages, including enhanced stability, targeted delivery, multiple therapeutic functions, and personalized therapy tailored to the severity. Despite these advantages, the development of biocompatible nanomedicines capable of selective accumulation in inflamed tissues and efficient inhibition of ROS-induced inflammatory signaling pathways remains a considerable challenge.

Healthcare utilization among foreign beneficiaries of the National Health Insurance program in Korea.

Background: To explore the factors related to healthcare utilization (both inpatient and outpatient services) among foreign beneficiaries of the National Health Insurance (NHI) in Korea.

Participants: The total foreign beneficiaries of the NHI in Korea 2022 were included (n = 1,386,329).

Variables: For the dependent variables, utilization and either hospital stays or count of visits were used.

Multilevel Analysis of the Relationship Between Prescribing Institutions and Medication Adherence Among Patients With Hypertension and Diabetes in Korea.

Objectives: This study investigated the relationship between prescribing institutions and medication adherence among patients newly diagnosed with hypertension and diabetes.

Methods: This study investigated patients with new prescriptions for hypertension and diabetes in Korea in 2019 with using data collected from general health screenings. A multilevel logistic regression model was applied to explore the relationship between patients' first prescribing institution and their medication adherence, defined as a medication possession ratio (MPR) over 80%.

Modified Epiblepharon Repair Preserving Orbicularis Oculi Muscle.

Methods: A retrospective review of was conducted of patients who received modified epiblepharon repair preserving orbicularis oculi muscle from April 2016 to October 2018. Removal of the orbicularis oculi muscle was minimally performed with eyelash rotating sutures and epicanthal weakening procedure. The preoperative severity of epiblepharon was classified according to skin fold height and cilia-corneal touch.

Clinicopathologic Characteristics Associated with Prognosis in Ocular Extranodal Marginal Zone B Cell Lymphoma.

: Extranodal marginal zone lymphoma of the mucosa-associated lymphoid tissue (MALT) type is the most common subtype of the ocular adnexal lymphoma. Despite its excellent prognosis, some patients experience partial remission or progressive disease. We aimed to evaluate clinicopathologic differences in the treatment responder group by comparing complete remission (CR) and non-complete remission (non-CR).

Association of blepharoptosis with refractive error in the Korean general population.

Background/objectives: We investigated the effect of blepharoptosis on refractive errors across different age groups in Korean population.

Subjects/methods: This cross-sectional study was performed with data obtained in the Korea National Health and Nutrition Examination Survey (KNHANES) from 2008 to 2012. A total of 33,103 participants were enroled in our study.

Astigmatism Associated with Allergic Conjunctivitis in Urban School Children.

Introduction: We first examined the association of an ocular refractive error with allergic conjunctivitis in school children and then examined this association in children attending a suburban school and an urban school.

Methods: We enrolled 426 children attending a primary school in a suburban area and 550 children attending a primary school in an urban area which had a higher level of air pollution. Allergic conjunctivitis was defined as the diagnosis of this condition at any time during a child's life.

Revision Surgery for Undercorrected Blepharoptosis After Frontalis Sling Operation Using Autogenous Fascia Lata.

Purpose: Undercorrected blepharoptosis can be encountered after frontalis sling operation. Revision surgery for undercorrection has commonly involved introducing a new sling material. We describe and evaluate a simple surgical technique to correct undercorrection by adjusting preexisting fascia.

Surgical treatment of unilateral severe simple congenital ptosis.

Unilateral congenital ptosis with poor levator function of ≤4 mm continues to be a difficult challenge for the oculoplastic surgeon. Surgical correction can be accomplished with unilateral frontalis suspension, maximal levator resection, or bilateral frontalis suspension with or without levator muscle excision of the normal eyelid. Bilateral frontalis suspension was proposed by Beard and Callahan to overcome the challenge of postoperative asymmetry, allowing symmetrical lagophthalmos on downgaze, postoperatively.

Maximal levator resection in unilateral congenital ptosis with poor levator function.

Background/aims: Surgical treatments for the correction of congenital ptosis with poor levator function, including frontalis suspension or maximal levator resection, remain controversial. We evaluated the postoperative surgical and cosmetic outcomes after maximal levator resection for unilateral congenital ptosis with poor levator function.

Methods: A retrospective, interventional case series was performed.

Macular Choroidal Thickness and Volume Measured by Swept-source Optical Coherence Tomography in Healthy Korean Children.

Purpose: To evaluate the thickness and volume of the choroid in healthy Korean children using swept-source optical coherence tomography.

Methods: We examined 80 eyes of 40 healthy children and teenagers (<18 years) using swept-source optical coherence tomography with a tunable long-wavelength laser source. A volumetric macular scan protocol using the Early Treatment Diabetic Retinopathy Study grid was used to construct a choroidal thickness map.

IgG4-related disease in idiopathic sclerosing orbital inflammation.

Aims: To investigate the frequency of IgG4-related disease (IgG4-RD) among patients previously diagnosed with idiopathic sclerosing orbital inflammation (ISOI), and to compare the clinical features and treatment outcomes of patients with ISOI associated with IgG4-RD and those without IgG4.

Methods: Retrospective clinicopathological series of 24 patients with ISOI diagnosed between June 2001 and June 2010. Biopsy specimens were immunostained for IgG-expressing and IgG4-expressing cells.

Preaponeurotic fat advancement in levator recession for treatment of upper eyelid retraction.

Background: Postoperative cosmetic deformities can be encountered after surgical treatments for upper eyelid retraction. The authors described a preaponeurotic fat advancement technique and investigated the effectiveness in patients who underwent levator recession for upper lid retraction.

Methods: This retrospective comparative case series included 44 patients (57 eyelids) who underwent levator recession surgery with (flap group, n = 31) or without (no-flap group, n = 26) the preaponeurotic fat advancement flap procedure.