Publications by authors named "Juho Paavola"

Article Synopsis
  • The study focused on aneurysmal intracerebral hemorrhage (aICH), highlighting the absence of personalized patient timelines and detailed brain imaging throughout treatment and recovery.
  • Researchers analyzed 54 patients who underwent surgical clipping for a specific type of aneurysm, compiling data from emergency calls to clinical outcomes using timeline and imaging panels.
  • Findings indicate that larger aICH volumes at the time of admission were linked to higher rates of rebleeds and mortality, emphasizing the need for timely intervention and enhanced imaging during surgery to monitor recovery.
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Article Synopsis
  • The study explores the relationship between pre-eclampsia and saccular intracranial aneurysms (sIAs), focusing on female patients, their relatives, and matched controls, to assess the prevalence of pre-eclampsia in these groups.
  • It analyzed data from 265 female sIA patients, their female relatives, and a control group, revealing a higher prevalence of pre-eclampsia in sIA patients (11%) compared to matched controls (6%).
  • The findings indicate that pre-eclampsia is more common among sIA patients, with familial occurrences observed in seven families, suggesting a need for further research into how pre-eclampsia may increase the risk of sIA rupture.
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Article Synopsis
  • - The study investigates the connection between having a family history of epilepsy in first-degree relatives and the likelihood of developing epilepsy after experiencing an aneurysmal subarachnoid hemorrhage (aSAH), which is a severe type of stroke often leading to significant complications.
  • - Researchers analyzed data from 760 aSAH survivors and compared it with a control group of 2,240 individuals, finding that 15% of aSAH patients developed epilepsy within about 7 months post-stroke, significantly higher than the rates in the general population and their relatives.
  • - The findings indicate that having at least one first-degree relative with epilepsy increases the risk of developing epilepsy after aSAH, with nearly 28% of patients
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Purpose: Our review of acute brain insult articles indicated that the patients' individual (i) timeline panels with the defined time points since the emergency call and (ii) serial brain CT/MRI slice panels through the neurointensive care until death or final brain tissue outcome at 12 months or later are not presented.

Methods: We retrospectively constructed such panels for the 45 aneurysmal subarachnoid hemorrhage (aSAH) patients with a secondary decompressive craniectomy (DC) after the acute admission to neurointensive care at Kuopio University Hospital (KUH) from a defined population from 2005 to 2018. The patients were indicated by numbers (1.

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Article Synopsis
  • - The study aimed to investigate the occurrence of pre-eclampsia, gestational hypertension, chronic hypertension, and gestational diabetes in pregnant women with saccular intracranial aneurysms (sIAs).
  • - Researchers analyzed medical records of 169 patients with sIA from 1990 to 2015, finding that 13% had pre-eclampsia and 19% experienced other hypertensive issues, compared to 5% and 10% in matched controls, respectively.
  • - The findings suggest pre-eclampsia is more common in women with sIA, and those with pre-eclampsia tended to have irregularly shaped aneurysms, indicating a need for further research on
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Background: To study the clinical condition of poor-grade aneurysmal subarachnoid hemorrhage (aSAH) patients alive at 3 years after neurointensive care.

Methods: Of the 769 consecutive aSAH patients from a defined population (2005-2015), 269 (35%) were in poor condition on admission: 145 (54%) with H&H 4 and 124 (46%) with H&H 5. Their clinical lifelines were re-constructed from the Kuopio Intracranial Aneurysm Database and Finnish nationwide registries.

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Background and Purpose- At acute phase and neurointensive care, patients with aneurysmal subarachnoid hemorrhage (aSAH) may become agitated or delirious. We found no previous studies on psychotic disorders or antipsychotic drug (APD) use by long-term aSAH survivors. We defined the APD use and its risk factors among 12-month survivors of aSAH in an Eastern Finnish population-based cohort with long-term follow-up.

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Background: The purpose of this population-based case-control study was to evaluate analgesic use after subarachnoid hemorrhage (SAH) caused by rupture of a saccular intracranial aneurysm (sIA).

Methods: The study consisted of 1187 patients alive 12 months after an sIA-SAH who were admitted to Kuopio University Hospital (KUH) between 1995 and 2014. Three controls, matched with age, sex, and birthplace, were included for each patient.

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