Subacute Neuropathy Post-Liver Transplantation in Zellweger Spectrum Disorder: A Case Report.

Peroxisome biogenesis disorders-Zellweger spectrum disorder (PBD-ZSD) is a rare genetic disease caused by mutations in the genes involved in peroxisome biogenesis. PBD-ZSD presentations vary in severity, and treatment of PBD-ZSD remains supportive focused on specific complications. A few reported cases of the use of liver transplantation to treat either neurological symptoms or liver dysfunction and cirrhosis in PBD-ZSD have been published.

Development and optimization of metal silicide EUV pellicle for 400W EUV lithography.

In the extreme ultraviolet lithography (EUVL) process, extreme ultraviolet (EUV) pellicles serve as thin, transparent membranes that shield the photomask (reticle) from particle contamination, thereby preserving photomask pattern integrity, reducing chip failure risks, and enhancing production yields. The production of EUV pellicles is highly challenging due to their mechanical fragility at nanometer-scale thicknesses and the need to endure the rigorous conditions of the EUVL environment, which include high temperatures and hydrogen radicals. Consequently, extensive research has been conducted on a variety of materials, such as carbon-based and silicon-based substances, for the development of EUV pellicles.

Analyzing the Effect of Social Distancing Policies on Traffic at Sinchon Station, South Korea, during the COVID-19 Pandemic in 2020 and 2021.

The COVID-19 pandemic is recognized as one of the most serious global health problems, and many countries implemented lockdown measures to mitigate the effects of the crisis caused by this respiratory infectious disease. In this study, we investigated the relationship between social distancing policies and changes in traffic volume in Sinchon Station, South Korea. We used an official COVID-19 report provided by the Korea Disease Control and Prevention Agency (KCDA) and Seoul Metropolitan Government (SMG) to review social distancing policies, and the changes in traffic patterns before and during the COVID-19 pandemic between January 2020 and November 2021 were analyzed.

Expansion of CD45RAFOXP3 regulatory T cells is associated with immune tolerance in patients with combined kidney and bone marrow transplantation.

Objectives: Simultaneous transplantation of a solid organ and bone marrow from the same donor is a possible means of achieving transplant tolerance. Here, we attempted to identify biomarkers that indicate transplant tolerance for discontinuation of immunosuppressants in combined kidney and bone marrow transplantation (CKBMT).

Methods: Conventional kidney transplant (KT) recipients ( = 20) and CKBMT recipients ( = 6) were included in this study.

Comparative study of human and cynomolgus T-cell depletion with rabbit anti-thymocyte globulin (rATG) treatment-for dose adjustment in a non-human primate kidney transplantation model.

Rabbit-antithymocyte globulin (rATG) is commonly used in kidney transplantation (KT) as an induction agent and is also commonly used in non-human primate (NHP) KT models. However, the optimal dose has not been reported. In this study, we evaluated which cumulative dose of rATG was most appropriate for transplantation in NHPs.

Simultaneously enhanced optical, electrical, and mechanical properties of highly stretchable transparent silver nanowire electrodes using organic surface modifier.

We report on a new surface modifier which simultaneously improves electrical, optical, and mechanical properties of silver nanowire-based stretchable transparent electrodes. The transparent electrodes treated with 11-aminoundecanoic acid achieve a low sheet resistance of 26.0 ohm/sq and a high transmittance of 90% with an excellent stretchability.

Effects of desensitizing agents for cervical dentin hypersensitivity: A randomized clinical trial.

Purpose: To evaluate the clinical efficacy of five commercially available desensitizing agents with different mechanisms applied to hypersensitive teeth.

Methods: A randomized clinical trial was conducted on subjects suffering dentin hypersensitivity in Korea University Guro Hospital from October 2013 to April 2015. A total of 64 subjects met the selection criteria and were randomly assigned to five commercially available desensitizing agents, and applied according to the manufacturers' instructions.

Bee venom acupuncture alleviates trimellitic anhydride-induced atopic dermatitis-like skin lesions in mice.

Background: Bee venom acupuncture (BVA), a novel type of acupuncture therapy in which purified bee venom is injected into the specific acupuncture point on the diseased part of the body, is used primarily for relieving pain and other musculoskeletal symptoms. In the present study, therapeutic potential of BVA to improve atopic dermatitis, a representative allergic dysfunction, was evaluated in the mouse model of trimellitic anhydride (TMA)-induced skin impairment.

Methods: Mice were treated with 5% TMA on the dorsal flank for sensitization and subsequently treated with 2% TMA on the dorsum of both ears for an additional 12 days after a 3-day interval.

Cell motility regulation on a stepped micro pillar array device (SMPAD) with a discrete stiffness gradient.

Our tissues consist of individual cells that respond to the elasticity of their environment, which varies between and within tissues. To better understand mechanically driven cell migration, it is necessary to manipulate the stiffness gradient across a substrate. Here, we have demonstrated a new variant of the microfabricated polymeric pillar array platform that can decouple the stiffness gradient from the ECM protein area.

Spatial control of chromosomal location in a live cell with functionalized magnetic particles.

Long-range chromosomal travel is a phenomenon unique to cell division. Methods for non-invasive, artificial manipulation of chromosomes, such as optical or magnetic tweezers, have difficulty in producing the motion of whole chromosomes in live cells. Here, we report the spatial control of chromosomes over 10 μm in a live mouse oocyte using magnetic particles driven by an external magnetic field.

Association of mid-pregnancy antioxidative vitamin and oxidative stress levels with infant growth during the first 3 years of life.

Objective: Numerous studies have revealed the impacts of maternal nutritional status on subsequent birth outcome, but much less is known about the long-term impacts on infant growth after birth. We investigated the association between maternal micronutrient levels/oxidative stress status in pregnancy and infant growth during the first 3 years of life.

Design: Prospective cohort study.

Effect of comorbidity on length of hospital stay and in-hospital mortality among unintentionally injured patients.

Objectives: Because comorbidity is a crucial issue in medical practice and research, this study evaluated the effect of comorbidity on the length of hospital stay and mortality among unintentionally injured patients.

Methods: Korea National Hospital Discharge In-depth Injury Survey 2005 data were used, and the odds ratios for in-hospital mortality and long hospital stay were estimated for injured patients with and without comorbidity. The factors evaluated were the injury mechanisms; patient age, sex and residence; and hospital size.

Change in causes of injury-related deaths in South Korea, 1996-2006.

Background: The aims of this study were to describe temporal patterns of injury-related mortality by sex, age group, and mechanism, and to identify changes in the leading causes of injury-related deaths in South Korea from 1996 through 2006.

Methods: This retrospective, descriptive study analyzed national data on all injury-related deaths reported in official death certificates from 1996-2006. Incidence rates of fatal injuries are presented as crude and age-standardized rates per 100 000 population, and percentage changes in injury-related mortalities over the 11-year period were calculated with respect to intention, sex, and age.

Injury prevention priority setting based on the National Injury Surveillance data in Korea.

For the reduction of injury burden, injury prevention efforts are essential. However, financial, material and human resources are far from sufficient, and this situation necessitates setting priorities for effective injury prevention. Hence, the aim of this study is to prioritise 13 injury mechanisms for prevention of injury using four injury burden criteria.

Parental socioeconomic status and unintentional injury deaths in early childhood: consideration of injury mechanisms, age at death, and gender.

The aim of this study was to determine whether the socioeconomic status (SES) of parents influences early childhood unintentional injury deaths for different injury mechanisms and the gender and age at death of the child. Study design is a population-based retrospective study. Death certificate data from 1995 to 2004 were linked to birth certificate data from 1995 to 1996 for each child who died when aged < or = 8 years.

Comparison of the risk-taking behaviours of children and the practices adopted by their caregivers for improving home safety.

Objectives: The objectives of this study were: (1) to describe the efforts of caregivers to provide a safe home environment for their children and the risk-taking behaviours of children; (2) to determine the efficacy of caregivers' practices for providing a safe environment on the risk-taking behaviours of children; (3) to identify factors influencing the home-safety practices adopted by caregivers for their children; and (4) to determine the information sources that caregivers use for preventing in-home injuries in their children.

Study Design: Cross-sectional study

Methods: The sample consisted of 563 pairs of elementary students and their caregivers, who were administered home-safety questionnaires at school and home, respectively. Five hundred and one matched pairs were included in the analysis.

Association of antioxidant vitamins and oxidative stress levels in pregnancy with infant growth during the first year of life.

Objective: Whereas there are numerous reports in the literature relating the impact of maternal nutritional status on subsequent birth outcome, much less is known about the long-term impact on infant growth after birth. Therefore, we conducted a prospective cohort study to investigate the association of maternal micronutrient status (vitamins A, C and E, folate) and oxidative stress status in pregnancy with infant growth during the first year of life.

Design: Prospective cohort study.

[Clustering of metabolic risk factors and its related risk factors in young schoolchildren].

Objectives: We wanted to determine the distribution of the clustering of the metabolic risk factors and we wanted to evaluate the related factors in young schoolchildren.

Methods: A cross-sectional study of metabolic syndrome was conducted in an elementary school in Seoul, Korea. We evaluated fasting glucose, triglyceride, HDL cholesterol, blood pressures and the body mass index, and we used parent-reported questionnaires to assess the potential risk factors in 261 children (136 boys, 125 girls).

Immersed finite element method and its applications to biological systems.

This paper summarizes the newly developed immersed finite element method (IFEM) and its applications to the modeling of biological systems. This work was inspired by the pioneering work of Professor T.J.

Risk factors for benign prostatic hyperplasia in South Korean men.

Objectives: Benign prostatic hyperplasia (BPH) is the most common prostate disease in middle-aged and elderly men, and leads to severe impairment in later life. Despite the significant effect on public health, the causes of BPH have received little attention. Identifying risk factors for BPH is crucial for understanding the etiology and for determining effective interventions or targeting strategies.

The relationship between PTC taster status and taste thresholds in young adults.

Objective: The aim of this study was to compare taste detection and recognition thresholds of young males and females, and young phenylthiocarbamide (PTC) "tasters" and "nontasters" for stimuli representing sweet, sour, bitter, salty, and umami classes of taste sensations.

Study Design: Thirty-eight men and 37 women (mean [SD] age = 24.5 [2.