Predictors of short-term recovery of urinary continence after radical prostatectomy.

Purpose: To evaluate treatment variables for early urinary continence status 6 weeks following radical prostatectomy.

Methods: In this retrospective analysis, 4,028 consecutive patients underwent open radical retropubic (RRP) or robot-assisted transperitoneal prostatectomy (RARP) at a single academic institution (07/2003-07/2013). After discharge, patients were offered 3-week treatment in a rehabilitation facility.

Comprehensive report on prostate cancer misclassification by 16 currently used low-risk and active surveillance criteria.

Unlabelled: What's known on the subject? and What does the study add? Prostate cancer characterisation, based on laboratory findings, clinical examination and histopathological cancer features that are used to define selection criteria for AS, is not ideal. Consequently, a panel of strict or more lenient criteria to select patients for AS have been published. Studies investigating the relationship between pretreatment variables and final pathology have been done in the past showing the risk of cancer misclassification for some criteria.

[The role of surgery in locally advanced prostate cancer].

Recent retrospective monocentric studies have demonstrated favorable 15-year cancer-specific survival (CSS) rates of up to 86% using radical prostatectomy as part of multimodal treatment in locally advanced prostate cancer (T3-4, N0, M0). Patients most likely to benefit from surgery include those with a biopsy Gleason score < or =8, a prostate-specific antigen level <20 ng/ml, and cT3a cancer. Patients must be informed that additional treatment after prostatectomy might be necessary (30-70%; radiotherapy, hormonal therapy).

Influence of nerve-sparing (NS) procedure during radical prostatectomy (RP) on margin status and biochemical failure.

Purpose: To evaluate whether nerve-sparing procedure itself is a risk factor for biochemical recurrence in carefully selected patients.

Material And Methods: We compared patients of our historical series who in retrospect were candidates for nerve-sparing (NS) procedure with a contemporary cohort of patients. With respect to stage migration and selection bias between these two groups we performed a multivariate analysis adjusting for all explanatory variables in the model.