Publications by authors named "Juergen A Ripperger"
Article Synopsis
- * Mice lacking the PER2 protein (Per2 (Brdm1)) show lower blood sugar levels, disrupted liver glycogen storage, and altered eating patterns compared to normal mice.
- * PER2 is vital for regulating enzymes involved in glycogen metabolism, suggesting it plays a key role in managing how the liver stores glucose during feeding and fasting times.
Mammalian circadian clocks restrict cell proliferation to defined time windows, but the mechanism and consequences of this interrelationship are not fully understood. Previously we identified the multifunctional nuclear protein NONO as a partner of circadian PERIOD (PER) proteins. Here we show that it also conveys circadian gating to the cell cycle, a connection surprisingly important for wound healing in mice.
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