Nebulization of corticosteroids to asthmatic children: large variation in dose inhaled.

Background And Objective: Despite problems associated with assessing the clinical effect and side effects of nebulized corticosteroids, little is known of the amount of drug that is inhaled by children with asthma or how this is affected by different drug formulations. The aim of this study was to test the hypothesis that children with asthma inhale the same proportion of the prescribed dose of nebulized fluticasone, beclomethasone dipropionate (BDP) and flunisolide.

Methods: The amount of nebulized drug that would have been inhaled by asthmatic children was captured on filters between the patient and nebulizer, and the amount contained in particles likely to reach the lung (i.

Nebulisation of corticosteroid suspensions and solutions with a beta(2) agonist.

The aim of this study was to determine the output of salbutamol nebulised in combination with either flunisolide or beclometasone dipropionate (BDP) from two different nebulisers under simulated breathing conditions. The BimboNeb and Nebula nebulisers were used to nebulise 3.0 mL of the two drug mixtures (salbutamol, 5000 microg plus either flunisolide, 600 microg, or BDP, 800 microg).

Enhanced delivery of nebulised salbutamol during non-invasive ventilation.

Non-invasive ventilation (NIV) is used to treat acute respiratory failure. Nebulised drugs can be delivered concurrently with NIV or during breaks from ventilatory support. We hypothesised that the amount of nebulised salbutamol inhaled when delivered via bi-level ventilation would be no different to the amount available directly from the same nebuliser.

The 2001 Kentucky Childrens Oral Health Survey: findings for children ages 24 to 59 months and their caregivers.

Purpose: This study was performed to provide a 2001 benchmark of oral health status of children in Kentucky with a comparison to the most recent state (1987) and national surveys.

Methods: Using Basic Screening Survey protocols for visual screenings, a sample of 572 children ages 24 to 59 months was screened in health department clinics and physicians' and pediatric dentists' offices across Kentucky after caregivers completed a questionnaire. Screeners were provided modified Association of State and Territorial Dental Directors training materials.