Preliminary testing of a patient decision aid for patients with relapsing-remitting multiple sclerosis.

Background: Multiple first-line disease modifying therapies (DMTs) are available for relapsing-remitting multiple sclerosis (RRMS), each with different characteristics. We developed an interactive patient decision aid (PtDA) to promote informed shared decision-making (SDM).

Objective: To test the preliminary effectiveness of the PtDA in participants with RRMS.

Variation in the Management of Pain, Agitation, and Delirium in Intensive Care Units in British Columbia.

Background: Pain, agitation, and delirium are associated with negative outcomes in critically ill patients. Reducing variation in pain, agitation, and delirium management among institutions could improve care.

Objectives: To define opportunities to improve pain, agitation, and delirium management in intensive care units in British Columbia, Canada.

Development and usability testing of a patient decision aid for newly diagnosed relapsing multiple sclerosis patients.

Background: Multiple sclerosis (MS) patients often struggle with treatment decisions, in part due to the increasing number of approved disease modifying therapies, each with different characteristics, and also since physicians can struggle to identify which of these characteristics matter most to each individual patient. Decision uncertainty can contribute to late treatment initiation and treatment non-adherence-causes of 'undertreatment' in MS. An interactive online patient decision aid that informs patients of their options, considers their individual preferences and goals, and facilitates conversations with their physicians, could improve how patients with relapsing forms of MS make evidence-based treatment decisions.

An update on the measurement of productivity losses due to rheumatoid diseases.

Many health systems are interested in the impact of disease and interventions on non-health outcomes. Over the last 10 years, work productivity has become one of the most important topics. This study was conducted to review guidelines for economic evaluations worldwide to identify how views on the types of productivity costs to be included differ across jurisdictions and to review recent trials that have measured productivity losses to identify trends and compare consistency with guidelines from different jurisdictions.