Publications by authors named "Judith Popp"
Dedifferentiated melanoma (DM) and undifferentiated melanoma (UM) is defined as a primary or metastatic melanoma showing transition between conventional and undifferentiated components (DM) or lacking histologic and immunophenotypic features of melanoma altogether (UM). The latter is impossible to verify as melanoma by conventional diagnostic tools alone. We herein describe our experience with 35 unpublished cases to expand on their morphologic, phenotypic, and genotypic spectrum, along with a review of 50 previously reported cases (total: 85) to establish the diagnostic criteria.
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- The study investigates the role of Trefoil factor family peptide 3 (TFF3) in the synovial membrane (SM) and synovial fluid (SF) of patients with osteoarthritis (OA) and rheumatoid arthritis (RA).
- It was found that TFF3 is present in both healthy and diseased SM, but only TFF1 and TFF2 were detected in SF samples from all groups, suggesting their origins may be from blood serum rather than joint tissue.
- The research highlights that TFF3 levels were significantly lower in OA patients compared to healthy individuals, while TFF2 was higher in RA samples, indicating these peptides might play a different role in joint diseases.