Publications by authors named "Judith Passildas"

Article Synopsis
  • - The study explored the effectiveness of combining curcumin with docetaxel for patients with advanced and metastatic breast cancer, focusing on whether this combination improved treatment response rates.
  • - Conducted across multiple centers, the research included 42 patients and aimed to compare the objective response rates and other clinical outcomes between the two treatment groups but found no significant differences.
  • - Ultimately, the study concluded that adding curcumin to docetaxel did not enhance efficacy and was deemed safe, leading to the decision to stop the trial due to lack of meaningful results, while suggesting further research with adjustments for more conclusive findings.
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Background: Currently, the long-term prognosis and survival rate of patients with high-grade glial tumors remains poor and there are no biomarkers. hPG (circulating progastrin) secreted into the blood by tumor cells has been widely studied in colorectal cancer. Its involvement in tumorigenesis has been demonstrated in the literature.

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Article Synopsis
  • The study focuses on establishing patient-derived xenografts (PDX) to better understand breast cancer, particularly from patients with triple negative or luminal B types during various treatment phases.
  • It aims to enroll 85 patients over three years, collecting tumor samples and additional blood for analysis, while tracking the histomolecular characteristics of the PDX to ensure accuracy.
  • The study, titled XENOBREAST, has received ethical approval and complies with international research guidelines, with plans for data publication in medical journals and presentations at conferences.
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Purpose: The proportion of older populations living with cancer is on the increase. Maintaining or improving their quality of life (QoL) has become an important goal in the treatment of cancer and has become an endpoint in clinical trials. Melatonin regulates a wide variety of physiological functions and is involved in the initiation of sleep and the improvement of QoL.

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Physical activity is known to prevent the occurrence of cancer and decrease the risk of breast cancer. At diagnosis of breast cancer, fewer than half of the patients reach the international recommendation for physical activity. However, breast cancer patients, and particularly HER2+ breast cancer patients, are exposed to treatment-induced cardiotoxicity because of a side effect of 2 molecules used in standard therapy to treat these tumors, i.

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Background: Young patients with breast cancer treated with chemotherapy can experience ovarian failure, which can lead to chemotherapy-induced menopause (CIM) impacting the quality of life (QoL). A prospective study was set out to evaluate the impact of CIM on QoL in women of childbearing age with non-metastatic breast cancer, and this article reports results of the interim analysis conducted to evaluate feasibility and to see preliminary results.

Patients And Methods: A total of 58 women (age, 18-46 years) with newly diagnosed breast cancer and treated with chemotherapy were eligible.

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Background: Weight changes during adjuvant treatment for early-stage breast cancer has been associated with a poor prognosis. The long-term evolution of body composition during adjuvant treatment for breast cancer, in particular, endocrine therapy, is not well known, and new data on this topic are required. The present study assessed the evolution of weight and body composition among 33 postmenopausal breast cancer patients receiving endocrine therapy after standard adjuvant chemotherapy that included taxanes.

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