Synopsis of recent research by authors named "Judith Niesen"
- Judith Niesen's research primarily focuses on the molecular mechanisms underlying brain tumors, particularly childhood medulloblastomas, and the role of specific genes and transcription factors in their development and progression.
- Recent findings indicate that overexpression of certain transcription factors leads to severe cerebellar malformations and potential tumor formation in experimental mouse models, while also emphasizing the impact of genetic mutations on tumor growth and metastasis.
- Additionally, Niesen's work highlights innovative methodologies, such as utilizing DNA methylation profiles for estimating infiltrating lymphocyte interactions in CNS tumors, and demonstrating the effectiveness of SNAP-Tag technology for measuring apoptotic changes in cancer cells.
