Publications by authors named "Judith M Estes"

Article Synopsis
  • Human Endogenous Retroviruses type K HML-2 (HK2) include newly discovered proviruses, K111 and K222, which are notably found in pericentromeric regions of the human genome.
  • Researchers utilized PCR and sequencing to analyze the K111 provirus across various ethnic groups and disease contexts.
  • The results show that a deletion of the K111 provirus is linked to increased severity in Cutaneous T-cell lymphoma (CTCL) among Caucasians and appears to influence T-cell survival in HIV infection, highlighting its evolutionary significance and origins out of Africa.
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The number of cancer survivors in the United States will continue to grow because of improved screening, early detection practices, and advances in treatment. The cancer experience has a significant impact on the patient and his or her family, which increases the risk for psychosocial distress. Untreated distress experienced by a patient with cancer contributes to poorer treatment adherence, medical outcomes, and quality of life.

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Purpose/objectives: To review radioimmunotherapy approaches for low-grade non-Hodgkin lymphoma (NHL) with a focus on tositumomab and iodine-131 tositumomab (Bexxar, Corixa Corporation, Seattle, WA, and GlaxoSmithKline, Philadelphia, PA). Nursing implications for Bexxar therapy are reviewed, including radiation safety, patient education, and the management of therapy-related toxicities.

Data Sources: Journal articles, published research data, and clinical experience.

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