Publications by authors named "Judith C S Holtjer"

Background: The global severity of SARS-CoV-2 illness has been associated with various urban characteristics, including exposure to ambient air pollutants. This systematic review and meta-analysis aims to synthesize findings from ecological and non-ecological studies to investigate the impact of multiple urban-related features on a variety of COVID-19 health outcomes.

Methods: On December 5, 2022, PubMed was searched to identify all types of observational studies that examined one or more urban exposome characteristics in relation to various COVID-19 health outcomes such as infection severity, the need for hospitalization, ICU admission, COVID pneumonia, and mortality.

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: The coronavirus disease 2019 (COVID-19) pandemic has led to the death of almost 7 million people, however, with a cumulative incidence of 0.76 billion, most people survive COVID-19. Several studies indicate that the acute phase of COVID-19 may be followed by persistent symptoms including fatigue, dyspnea, headache, musculoskeletal symptoms, and pulmonary functional-and radiological abnormalities.

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Article Synopsis
  • The study aims to explore the relationship between cardiac autonomic function (measured by heart rate and heart rate variability) and blood pressure, particularly focusing on diastolic blood pressure (DBP).
  • Observational analyses indicated that while heart rate (HR) was positively associated with BP, other HRV traits showed negative associations, suggesting a complex interaction.
  • Genetic analyses supported these observations, revealing a potential causal effect of HRV traits on DBP, without evidence of blood pressure affecting HRV traits.
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Background: COPD and adult-onset asthma (AOA) are the most common noncommunicable respiratory diseases. To improve early identification and prevention, an overview of risk factors is needed. We therefore aimed to systematically summarise the nongenetic (exposome) risk factors for AOA and COPD.

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