Publications by authors named "Judith C Bruner"
Article Synopsis
- Effective detection of SARS-CoV-2 variants through wastewater analysis can complement existing clinical testing methods, especially in resource-limited areas where traditional testing may be biased.* -
- The study implemented improved virus concentration techniques and software to enhance the sequencing of multiple virus strains from wastewater, resulting in high-resolution data over 295 days at a university and its surrounding county.* -
- Wastewater surveillance identified emerging variants up to 14 days earlier than clinical methods and revealed instances of virus spread that clinical testing missed, highlighting its potential for public health monitoring.*
As SARS-CoV-2 continues to spread and evolve, detecting emerging variants early is critical for public health interventions. Inferring lineage prevalence by clinical testing is infeasible at scale, especially in areas with limited resources, participation, or testing/sequencing capacity, which can also introduce biases. SARS-CoV-2 RNA concentration in wastewater successfully tracks regional infection dynamics and provides less biased abundance estimates than clinical testing.
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