A pilot study of sleep, cognition, and respiration under 4 weeks of intermittent nocturnal hypoxia in adult humans.

Study Objectives: A pilot study to examine the effects of intermittent nocturnal hypoxia on sleep, respiration and cognition in healthy adult humans.

Methods: Participants were eight healthy, non-smoking subjects (four male, four female), mean age of 26.4+/-5.

Nocturnal hypoxia exposure with simulated altitude for 14 days does not significantly alter working memory or vigilance in humans.

Study Objectives: To assess the effect of 2 weeks of nocturnal hypoxia exposure using simulated altitude on attention and working memory in healthy adult humans.

Design: Prospective experimental physiological assessment.

Setting: General Clinical Research Center.