Over‐Representation of Extremely Wealthy Neighborhood Social Exposomes for Brain Donors within Alzheimer’s Disease Research Center Brain Banks assessed by the Neighborhoods Study.

Background: Adverse social exposome (indexed by national Area Deprivation Index [ADI] 80‐100 or ‘high ADI’) is linked to structural inequities and increased risk of Alzheimer’s disease neuropathology. Twenty percent of the US population resides within high ADI areas, predominantly in inner cities, tribal reservations and rural areas. The percentage of brain donors from high ADI areas within the Alzheimer’s Disease Research Center (ADRC) brain bank system is unknown.

Adverse Social Exposome by Area Deprivation Index (ADI) and Alzheimer’s Disease and Related Dementias (ADRD) Neuropathology for a National Cohort of Brain Donors within the Neighborhoods Study.

Background: Adverse social exposome (indexed by high national Area Deprivation Index [ADI]) is linked to structural inequities and increased risk of clinical dementia diagnosis, yet linkage to ADRD neuropathology remains largely unknown. Early work from single site brain banks suggests a relationship, but assessment in large national cohorts is needed to increase generalizability and depth, particularly for rarer neuropathology findings.

Objective: Determine the association between adverse social exposome by ADI and ADRD neuropathology for brain donors from 21 Alzheimer’s Disease Research Center (ADRC) brain banks as part of the on‐going Neighborhoods Study.

Speech correlates of neuropsychiatric symptoms in older adults.

Background: Neuropsychiatric symptoms (NPS) including depression and apathy, are common in dementia and profoundly affect both patients and caregivers. These symptoms can manifest early and can be indicative of the disease progression. The existing tools for measuring NPS lack objectivity and are not sensitive enough to detect subtle changes in the earlier stages of dementia.

Association between Amyloid Burden and Health‐Related Resource Use.

Background: Several disease modifying treatment (DMT) in early AD have shown effectiveness in reducing rate of decline on cognition and function. Earlier analyses using participants who are likely targets for clinical trial and treatment showed treatment effects may have important effects on patients’ work capacity and need for informal care. However, amyloid pathology was not examined.

The use of a testimonial video featuring diverse ADRC participants to change research attitudes in the elderly community.

Background: Black, Latinx, and Asian community elders remain underrepresented in dementia research. This study explored whether a video created to promote diversity in research by featuring underrepresented ADRC participants would change attitudes about research generally (e.g.

Digital Elder Abuse Intervention for Early Detection of Abuse in Older Adults Living with Dementia.

Background: Elder abuse (EA) is a major public health problem and older people living with dementia (PLWD) are not likely to self‐report EA. As a result, identification of EA remains low, and providers often miss the opportunity to identify EA during Emergency Department (ED) visits. We present a pilot study on adapting an evidence‐informed intervention to motivate PLWD to self‐report abuse despite existing cognitive challenges.

Technology Use Amongst Older Adults with and without Cognitive Impairment: Results from the ‘Validation of Video Administration of a Modified UDSv3 Cognitive Battery (VCog)’ Study.

Background: Video interfacing is increasingly being used in research and health care. The ‘VCog’ Study seeks to determine whether remote research cognitive assessments are reliable and valid by directly comparing results from in‐person administration of a standardized cognitive battery to the same battery administered remotely by video. The study also assesses technology use and comfort amongst participants of varying levels of cognitive impairment.

Smartphone ownership and usage in Chinese- and English-speaking older adults.

Background: Data collection by smartphone is becoming more widespread in healthcare research. Previous studies reported racial/ethnical differences in the use of digital health technology. However, cross-language group comparison (Chinese- and English-speaking older adults) were not performed in these studies.

Alcohol use disorders in geriatrics.

Alcohol use disorders cause significant morbidity and mortality in the geriatric population. This review article begins with a hypothetical case for illustration, asking what the primary care physician could do for a geriatric patient with alcohol abuse over a course of four office visits. Various aspects of alcohol use disorders in the geriatric population are reviewed, such as range of alcohol use, epidemiology, medical/psychiatric impact, detection, comprehensive treatment planning, modalities of psychotherapy, medication management, and resources for clinicians/patients.

Update on neuropsychiatric symptoms of dementia: evaluation and management.

The neuropsychiatric symptoms of dementia can lead to a decreased quality of life, rapid cognitive decline, early patient institutionalization, tremendous caregiver burden, and increased cost of care. A thorough assessment to evaluate and treat any underlying causes of symptoms is essential. With the lack of an approved drug to treat the neuropsychiatric symptoms of dementia, nonpharmacologic interventions take on added importance.