Maturation of mismatch negativity: a scalp current density analysis.

Objective: Auditory evoked potentials provide the opportunity to better understand the central processing of auditory stimuli, which is the basis of speech and language perception. The purpose of this study was to examine maturational changes in the topography of one of these auditory evoked potentials, the mismatch negativity (MMN), using scalp current density (SCD) analysis.

Design: Subjects were children ages 4 to 11 yr (N = 53), and adults (N = 12).

Maturation of mismatch negativity in typically developing infants and preschool children.

Objective: 1) To determine whether an adult-like mismatch negativity (MMN) can be reliably elicited in typically developing awake infants and preschool children, and if so 2) to examine whether maturational changes exist in MMN latencyand amplitude.

Design: Two experiments were designed to elicit MMN using an "oddball" paradigm. In Experiment 1, a 1000-Hz tone served as the standard stimulus and a 1200-Hz tone as the deviant.