Publications by authors named "Judit Sahin-Toth"

Staphylococcus aureus is one of the most important human pathogenic bacteria and environmental surfaces play an important role in the spread of the bacterium. Presence of S. aureus on children's playgrounds and on toys was described in international studies, however, little is known about the prevalence and characteristics of S.

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Neisseria meningitidis causes life-threatening invasive meningococcal disease (IMD) with high mortality worldwide. Asymptomatic pharyngeal meningococcus colonisation is an important reservoir for the spread of the bacterium. The aim of this study was to determine N.

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Methicillin-resistant bearing the gene (-MRSA) has been reported from animals and humans in recent years. This study describes the first -MRSA isolates of human and equine origin in Hungary (two isolates from horses and one from a veterinarian, who treated one of the infected horses, but was asymptomatic). MRSA isolates were identified by cultivation and PCR detection of the species-specific gene and / methicillin resistance genes.

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In 2011 mecC, a new mecA gene homologue, was described in a bovine isolate in the UK. Since then, mecC-positive methicillin-resistant Staphylococcus aureus (mecC-MRSA) has also been found in wild animals. An especially high prevalence of mecC-MRSA has been reported among hedgehogs in Sweden (64%) and Denmark (61%).

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Background: Staphylococcus aureus and S. pseudintermedius are the two most common coagulase positive staphylococci (CPS). S.

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Article Synopsis
  • The study analyzes Staphylococcus aureus bloodstream infections, focusing on the differences between methicillin-resistant (MRSA) and methicillin-sensitive (MSSA) strains.
  • The researchers examined 306 isolates from Hungary to assess antibiotic resistance, virulence factors, and their impact on 30-day mortality rates among patients.
  • Findings revealed that specific MRSA clones had varying resistance patterns and mortality rates, with MRSA showing higher resistance to common antibiotics and a higher associated mortality rate compared to MSSA.
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Background: The nasopharynx can from time to time accommodate otherwise pathogenic bacteria. This phenomenon is called asymptomatic carriage. However, in case of decreased immunity, viral infection or any other enhancing factors, severe disease can develop.

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Young children - the main asymptomatic carriers of pneumococcus - are often the source of pneumococcal infections. PCV13 replaced PCV7 in 2010 in Hungary and it became a mandatory vaccine in 2014. In this work we surveyed the effect of vaccination in three groups: in healthy children under 7 years; in children of the same age but infected with pneumococcus (P1); in older patients (P2) who were very likely not vaccinated.

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We collected nasal samples from 1,390 healthy 3-7 years old children in Szolnok city, Hungary, in 2012. We detected 476 Staphylococcus aureus isolates from 474 children. In two occasions, two different S.

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Article Synopsis
  • * One methicillin-sensitive catalase-negative S. aureus (CNSA) strain was found, featuring a unique mutation in the katA gene that truncates the protein and shows resistance to penicillin and erythromycin, but sensitivity to other antibiotics.
  • * This CNSA strain, belonging to a globally widespread sequence type (ST5), is novel as it comes from a symptomless carrier and contradicts prior beliefs about catalase being essential for nasal colonization, marking the first such report
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