Detecting Primary Progressive Aphasia Atrophy Patterns: A Comparison of Visual Assessment and Quantitative Neuroimaging Techniques.

Background: There are now clinically available automated MRI analysis software programs that compare brain volumes of patients to a normative sample and provide -score data for various brain regions. These programs have yet to be validated in primary progressive aphasia (PPA).

Objective: To address this gap in the literature, we examined Neuroreader -scores in PPA, relative to visual MRI assessment.