Antiulcerogenic activity of the essential oil of Hyptis martiusii Benth. (Lamiaceae).

Ethnopharmacological Relevance: Hyptis martiusii (Lamiaceae), popularly known as "cidreira-do-mato" or "cidreira-brava", grows in abundance in the Northeast region of Brazil, where its leaves are traditionally used in folk medicine in the treatment of intestinal and stomach diseases. The aim of this study was to characterize the chemical constituents and to evaluate the anti-ulcerogenic activity of the essential oil of the leaves of Hyptis martiusii (EOHM) in in vivo models of experimental ulcers in rodents.

Materials And Methods: EOHM was obtained by hydrodistillation and analyzed by gas chromatography-mass spectrometry (GC-MS).