Publications by authors named "Juanzi Yang"
Article Synopsis
- Co-amorphous (CM) technology helps improve the solubility of insoluble drugs, but gelation during dissolution can negatively affect their performance; hence, designing effective CM systems is crucial.*
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- In a study on TAX and OMT, although the CM systems gelled during dissolution, they significantly enhanced the solubility and dissolution of TAX compared to its crystalline form, indicating promising solubilization mechanisms.*
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- The study confirmed complex formation between TAX and OMT, showed their anti-crystallization properties through various characterization techniques, and demonstrated that the bioavailability of TAX was about 5.5 times higher in its CM form in rats, highlighting the effectiveness of CM systems for drug absorption.*
