A randomized study on the impact of optimized modified ultrafiltration on the physiological parameters of infants and children undergoing a cardiopulmonary bypass.

Background: The aim of this study is to assess the impact of optimized modified ultrafiltration (OMUF) on the physiological parameters of infants and children undergoing cardiopulmonary bypass (CPB).

Methods: In this randomized clinical trial, 30 pediatric patients were recruited and allocated into the experimental and control groups, each comprising of 15 patients. The experimental group underwent OMUF prior to the termination of CPB and extubation, while the control group received conventional modified ultrafiltration (MUF).

The Effect of Optimized Ultrafiltration on Perioperative Pulmonary Function During Cardiopulmonary Bypass in Infants Under 10 kg.

This study aims to investigate the effect of optimized ultrafiltration on perioperative electrolytes, acid-base balance, and pulmonary function during cardiopulmonary bypass (CPB) in infants with low body weight (under 10 kg), using traditional balanced ultrafiltration and modified ultrafiltration. A total of 30 children who underwent surgical correction for congenital heart disease in Changzhou Children's Hospital between January 2018 and December 2019 were randomly divided into two groups. In the treatment group, ultrafiltration pre-treatment was carried out with blood-containing priming fluid prior to CPB.