Publications by authors named "Juana Esther Gonzalez-Ulivarri"

Article Synopsis
  • Acute lymphoblastic leukemia (ALL) is linked to both genetic and environmental factors, with single nucleotide polymorphisms (SNPs) in specific genes potentially increasing risk in pediatric populations in Mexico.
  • A multicenter study was conducted comparing children diagnosed with ALL to healthy controls, examining the impact of SNPs rs2910164, rs12803915, rs11614913, and rs3746444 through DNA analysis.
  • The results indicated a significant association of the rs3746444 SNP with a higher risk of developing ALL, particularly in males, highlighting the need for further research on the genetic mechanisms behind ALL.
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Acute lymphoblastic leukemia (ALL) is the main type of cancer in children. In Mexico and other Hispanic populations, the incidence of this neoplasm is one of the highest reported worldwide. Functional polymorphisms of various enzymes involved in the metabolism of xenobiotics have been associated with an increased risk of developing ALL, and the risk is different by ethnicity.

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Background And Aims: Occupational exposure of parents to carcinogens is of great interest in the etiology of leukemias. Evidence of the impact of such exposure on infants or small children is scarce. Here we estimated whether occupational exposure of parents to carcinogens could be a risk factor for leukemias in their children.

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