Publications by authors named "Juan-ni Gong"
Article Synopsis
- - This study analyzed 64 patients with Takayasu's arteritis and pulmonary artery involvement to differentiate between active and inactive disease stages and find better markers for disease activity.
- - Results showed that active stage patients were younger and exhibited symptoms like fever and chest pain more frequently, alongside higher inflammatory markers and pulmonary artery wall thickening compared to inactive patients.
- - The study concluded that chest pain, increased platelet count, and pulmonary artery wall thickening could serve as new indicators of disease activity, with active patients showing better right heart function and lower pulmonary vascular resistance.
Long-term Outcomes and Predictors of Chronic Thromboembolic Pulmonary Hypertension After Pulmonary Endarterectomy.
Clin Appl Thromb Hemost
December 2022
Background: Pulmonary endarterectomy (PEA) is the preferred treatment for CTEPH patients which can significantly improve symptoms and pulmonary hemodynamics. Therefore, this retrospective study evaluated the long-term outcomes after pulmonary endarterectomy (PEA) and analyze the predictors of long-term outcomes for chronic thromboembolic pulmonary hypertension (CTEPH).
Methods: From 2002-2020, 76 CTEPH patients successfully discharged after PEA in Beijing Chaoyang Hospital were followed-up by scheduled clinical visits or telephone interviews.
Background: The feasibility and significance of imaging pulmonary artery (PA) remodeling with Ga-fibroblast activating protein inhibitor (FAPI) in patients with chronic thromboembolic pulmonary hypertension (CTEPH) have not yet been addressed.
Methods: Ga-FAPI-04 uptake in the PA and ascending artery was evaluated in 13 patients with CTEPH and 13 matched non-CTEPH controls. The correlations of PA Ga-FAPI-04 uptake and remodeling parameters derived from right heart catheterization (RHC) were analyzed.
Imaging of cardiac fibroblast activation in patients with chronic thromboembolic pulmonary hypertension.
Eur J Nucl Med Mol Imaging
March 2022
Purpose: The aim of this study was to explore the association of cardiac fibroblast activation with clinical parameters and cardiovascular magnetic resonance (CMR) imaging parameters in patients with chronic thromboembolic pulmonary hypertension (CTEPH).
Methods: Thirteen CTEPH patients were prospectively enrolled. All of the patients underwent cardiac Gallium-labelled fibroblast activation protein inhibitor ( Ga-FAPI-04)-positron emission tomography/computed tomography (PET/CT), right heart catheterisation, and echocardiography, and 11 of them additionally underwent CMR.
A definitive diagnosis of heparin-induced thrombocytopenia (HIT) is difficult to make, especially in patients undergoing cardiac surgery. In this retrospective cohort study, we assessed the platelet count trends and the response to fondaparinux in a population of patients of suspected HIT after pulmonary endarterectomy (PEA). Patients enrolled in this study were over the age of 18 years, and survived longer than 7 days after PEA between January 1, 2011 and December 31, 2015.
View Article and Find Full Text PDFAims: To explore the value of 18F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) in the detection of active pulmonary artery (PA) lesions in patients with Takayasu's arteritis (TA).
Methods And Results: Consecutive TA patients with PA involvement were prospectively recruited. Clinical activity was assessed according to the National Institutes of Health (NIH) criteria.
Figure c of the original version of this article was not converted properly. Correct figure is presented here. The original article has been corrected.
View Article and Find Full Text PDFTo determine the value of F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) in differentiating malignancy of pulmonary artery (PA) from pulmonary thromboembolism (PTE) based on a larger number of cases by pooling our cases and those from the literature. Consecutive patients with a PA lesion who had undergone F-FDG PET/CT in our hospital were retrospectively reviewed. Moreover, PubMed, Embase, and Medline were searched for literature reporting individual maximum standardised uptake value (SUV) of the malignant PA lesion and/or PTE.
View Article and Find Full Text PDFBackground: The clinical significance of acute vasoreactivity testing (AVT) in patients with chronic thromboembolic pulmonary hypertension (CTEPH) remains unclear. We analyzed changes in hemodynamics and oxygenation dynamics indices after AVT in patients with CTEPH using patients with pulmonary arterial hypertension (PAH) as controls.
Methods: We analyzed retrospectively the results of AVT in 80 patients with PAH and 175 patients with CTEPH registered in the research database of Beijing Chao-Yang Hospital between October 2005 and August 2014.
Background: Inoperable chronic thromboembolic pulmonary hypertension (CTEPH) is a severe clinical syndrome characterized by right cardiac failure and possibly subsequent liver dysfunction. However, whether serum markers of liver dysfunction can predict prognosis in inoperable CTEPH patients has not been determined. Our study aimed to evaluate the potential role of liver function markers (such as serum levels of transaminase, bilirubin, and gamma-glutamyl transpeptidase [GGT]) combined with 6-min walk test in the prediction of prognosis in patients with inoperable CTEPH.
View Article and Find Full Text PDF[Evaluation of the diagnostic value of adenosine deaminase activity in tuberculous pleuritis].
Zhonghua Jie He He Hu Xi Za Zhi
April 2010
Objective: To investigate the clinical value of pleural fluid adenosine deaminase (ADA) activity in differentiating tuberculous pleural effusions (TPE) from malignant effusions.
Methods: The serum and pleural adenosine deaminase activity of 91 cases confirmed by pleural biopsy through medical thoracoscopy were retrospectively analyzed. TPE was confirmed in 49 cases and malignant effusion in 42 cases.