Coypu (Myocastor coypus bonaeriensis) Ovarian Morphology During the Oestrous Cycle.

The coypu (Myocastor coypus bonariensis) is an annual polyestrous hystricomorph rodent with variable-length oestrous cycles, which ovarian histoarchitecture during this period is not fully described. This study analyses variations in ovarian morphology during the oestrous cycle, focusing on follicular development and atresia. Eighteen sexually mature virgin females aged 7-9 months, weighing 4.

Self-Assembled Tetrahedral [CrL] Cage Displaying Near-Infrared Spin-Flip Photoluminescence.

The thermodynamically controlled self-assembly of bis-bidentate quaterpyridine ligand, L = 2,2':5',5″:2″,2‴-quaterpyridine, with Cr and subsequent oxidation to Cr yields the first photoluminescent tetrahedral [CrL] molecular cage. Single-crystal X-ray diffraction reveals the presence of two homochiral cages (ΛΛΛΛ and ΔΔΔΔ) in the unit cell that crystallize as a racemic mixture. Additionally, a PF anion is observed inside the cavity, in line with isostructural cages built with Ni or Fe.

Biomechanical and histological evaluation of a prototype bovine pericardial patch for veterinary abdominal surgery: An approximation study.

In veterinary medicine, especially within large animal medical and surgical clinics, addressing cavitary defects is a primary concern. In bovines, umbilical hernias are the most common defect, and surgical repair often necessitates the use of prosthetic materials. However, there is a high rate of recurrence with sutures or synthetic meshes, largely due to tissue contamination.

Rapid method for paraffin embedding of precision-cut liver slices.

Precision-cut liver slices (PCLS) are tissue explants extensively used as an ex vivo model for metabolism and toxicity studies. When in vitro assays are conducted, it is imperative to perform a histomorphological evaluation as part of the viability analyses throughout the assay time. It is considered that good quality PCLS histological sections are difficult to obtain because they are hard to manipulate, and may shrink or fold during processing.

Exploring precision-cut liver slices for comparative xenobiotic metabolism profiling in swine and cattle.

In vitro systems are useful tools for unravelling species differences in xenobiotic metabolism.The current work aimed to validate the technique of precision-cut liver slices (PCLS) for comparative studies on xenobiotic metabolism in swine and cattle.PCLS from swine (n = 3) and cattle (n = 3) were produced using a Brendel-Vitron Tissue Slicer and cultured for 6 h.

Luminescence and Excited-State Reactivity in a Heteroleptic Tricyanido Fe(III) Complex.

Harnessing sunlight via photosensitizing molecules is key for novel optical applications and solar-to-chemical energy conversion. Exploiting abundant metals such as iron is attractive but becomes challenging due to typically fast nonradiative relaxation processes. In this work, we report on the luminescence and excited-state reactivity of the heteroleptic [Fe(pzTp)(CN)] complex (pzTp = tetrakis(pyrazolyl)borate), which incorporates a σ-donating trispyrazolyl chelate ligand and three monodentate σ-donating and π-accepting cyanide ligands.

A feasible method for llama embryo paraffin embedding.

Maternal recognition of pregnancy in llamas would be related to a still-unknown signal secreted by the embryo to extend the corpus luteum lifespan. In order to study llamas reproductive physiology and early pregnancy aspects, research on embryos between 8 and 12 days post-mating is essential. However, there is a lack of information on llama embryo paraffin embedding, a procedure that exhibits difficulties, mostly for embryo manipulation.

Current knowledge about the processes of luteolysis and maternal recognition of pregnancy in camelids.

Camelids have many unique reproductive features that considerably differ from those of other domestic species. Females are induced ovulators with subsequent development of a corpus luteum (CL) with a short lifespan. Plasma progesterone concentration starts to increase on day 4, peaks on day 8-9 and, in non-pregnant animals, basal concentration is reached around day 10-11 post-induction of ovulation.

Real-World Evidence of Epidemiology and Clinical Outcomes in Multiple Myeloma, Findings from the Registry of Hemato-Oncologic Malignancies in Colombia, Observational Study.

Introduction/background: Multiple Myeloma (MM) is a plasma cell derived clonal disorder that represents around 1% of all newly diagnosed neoplasms. Limited data regarding MM treatment in Latin America is available, and access to novel agents for a substantial portion of the population is limited by their high costs.

Materials (or Patients) And Methods: RENEHOC is a bidirectional (retrospective and prospective) multicenter observational registry of hematological malignancies in Colombia.

Monitoring spin-crossover phenomena Re(I) luminescence in hybrid Fe(II) silica coated nanoparticles.

Bare (1) and silica coated (1@SiO2) spin crossover (SCO) nanoparticles based on the polymer {[Fe(NHTrz)](BF)} have been prepared following a water-in-oil synthetic procedure. For 1, the critical temperatures of the spin transition are ↓ = 214.6 K and ↑ = 220.

Seven-coordinate Ln complexes assembled from a bulky acacH ligand: their synthesis, structure, photoluminescence and SMM behaviour.

The reaction of a bulky acetyl acetone ligand 1,3-dimesitylpropane-1,3-dione (MesacacH) with hydrated lanthanide chlorides in the presence of tetramethylammonium hydroxide afforded a new family of neutral mononuclear LnIII complexes [Ln(Mesacac)3(DMF)] (Ln = Dy (1); Tb (2); Y0.91Dy0.09 (3); and Er (4)).

Effect of Mycobacterium cell wall fraction on endometrial histomorphometry of mares resistant and susceptible to persistent breeding-induced endometritis.

Mycobacterium cell wall fraction (MCWF) is a biological component made up of molecules with immunostimulant properties, which is therapeutically used to modulate persistent breeding-induced endometritis (PBIE). The aim of this study was to analyze the effect of this immunomodulator on the endometrial histological structure during the diestrus of PBIE-resistant and -susceptible mares that either received treatment with MCWF or not. The experiment was conducted with 10 resistant mares (RM) and 9 susceptible mares (SM).

Selective block of grey communicantes in upper thoracic sympathectomy. A feasibility study on human cadaveric specimens.

Sympathetic chain interruption is the gold standard treatment for essential hyperhidrosis. Postoperative compensatory hyperhidrosis, the main reason for patients' dissatisfaction, is reduced by selectively lesioning white and grey rami communicantes (ramicotomy). To develop an endoscopic surgical technique that interrupts only T and T grey rami communicantes to minimize compensatory hyperhidrosis.

Mononuclear lanthanide complexes assembled from a tridentate NNO donor ligand: design of a Dy single-ion magnet.

The reaction of a tridentate NNO donor ligand, 4-nitro-2-((2-(pyridine-2-yl)hydrazono)methyl)phenol (HL) with lanthanide(iii) nitrates in the presence of triethylamine afforded a new family of neutral mononuclear LnIII complexes [Ln(NO3)(L)2(HOCH3)] (Ln = Gd; (1) Tb; (2), Dy; (3), and Ho (4). The mononuclear complexes were structurally characterized by single crystal X-ray diffraction studies which revealed a spherical tricapped trigonal prism geometry with a pseudo D3h symmetry around the LnIII centre. Static (dc) and dynamic (ac) magnetic studies have been performed on these complexes.

A Chiral Bipyrimidine-Bridged Dy SMM: A Comparative Experimental and Theoretical Study of the Correlation Between the Distortion of the DyO6N2 Coordination Sphere and the Anisotropy Barrier.

Chiral bipyrimidine-bridged dinuclear Ln complexes of general formula [(μ-bipym){((+)-tfacam)Ln}] and [(μ-bipym){((-)-tfacam)Ln}], have been prepared from the assembly of Ln(AcO)·nHO (Ln = Dy, Gd), (+)/(-)-3-(trifluoroacetyl)camphor enantiopure ligands ((+)/(-)-Htfacam) and bipyrimidine (bipym). The structure and chirality of these complexes have been supported by single-crystal X-Ray diffraction and circular dichroism. The study of the magnetic properties of the Gd complexes revealed a very weak antiferromagnetic interaction between the Gd ions through the bipyrimidine bridging ligand.

High frequency of lumbar fusion in patients denied surgical treatment of the sacroiliac joint.

Purpose: Effective treatment of medical conditions relies on proper diagnosis. Clinical trials show the safety and effectiveness of sacroiliac joint (SIJ) fusion in patients with chronic SI joint dysfunction. To what extent is the condition under recognised?

Objective: To determine whether under recognition of SIJ pain affects healthcare trajectories in Spanish patients with low back pain.

Field-Induced Single Molecule Magnets of Phosphine- and Arsine-Oxides.

The coordination chemistry of dysprosium and terbium toward phosphine and arsine oxides was further explored. Thus, the new nitrate [M(NO)(PhPO)] ( = Tb, ; Dy, ), [Dy(NO)(EtOH)(PhXO)] ( = P, ; As, ), chloride [DyCl(PhAsO)]Cl (), triflate [Dy(OTf)(MePhPO)]OTf (; OTf = triflate) and hexafluoroacetylacetonate [M(hfa)(PhPO)] (hfa = hexafluoroacetylacetonate; = Tb, ; Dy, ) complexes were isolated and fully characterized. The crystal structures of ·CHCN, ·CHCN, , ·2.

Tb, Dy, and ZnDy Complexes Showing the Unusual Versatility of a Hydrazone Ligand toward Lanthanoid Ions: a Structural and Magnetic Study.

Three dinuclear complexes, [Tb(Hdaps)(CHOH)(HO)](Cl) (TbCl), [Dy(Hdaps)(Cl)(CHOH)(HO)]Cl (DyCl), and [Dy(Hdaps)(HO)](CFSO) (DyCFSO), as well as the heterohexanuclear compound [ZnDy(daps)(Hdaps)(Cl)(OH)(CHOH)(HO)] (ZnDy) (Hdaps: 2,6-bis(1-salicyloylhydrazonoethyl)pyridine), which crystallize with different lattice molecules, show their hexa- or heptadentate hydrazone ligands acting with hitherto unknown μ-κ:κ, μ-κ:κ:κ, μ-κ:κ:κ:κ, or μ-κ:κ:κ:κ bridging modes. The single X-ray crystal structures of the dinuclear complexes show nine-coordinated N O environments for lanthanoid atoms in TbCl and DyCFSO, with distorted geometries, between spherical capped square antiprism and muffin-like, while the dysprosium atoms in DyCl are eight-coordinated, with distorted triangular dodecahedron geometries. In the case of ZnDy, both eight-coordinated, O and O Cl, as well as nine-coordinated N O environments coexist in the crystal structure, with biaugmented trigonal prism, triangular dodecahedron, and muffin-like pseudogeometries.

Designing a Dy Single-Molecule Magnet with Two Well-Differentiated Relaxation Processes by Using a Nonsymmetric Bis-bidentate Bipyrimidine- N-Oxide Ligand: A Comparison with Mononuclear Counterparts.

Herein we report a dinuclear [(μ-mbpymNO){(tmh)Dy}] (1) single-molecule magnet (SMM) showing two nonequivalent Dy centers, which was rationally prepared from the reaction of Dy(tmh) moieties (tmh = 2,2,6,6-tetramethyl-3,5-heptanedionate) and the asymmetric bis-bidentate bridging ligand 4-methylbipyrimidine (mbpymNO). Depending on whether the Dy ions coordinate to the N^O or N^N bidentate donor sets, the Dy sites present a NO ( D geometry) or NO ( D) coordination sphere. As a consequence, two different thermally activated magnetic relaxation processes are observed with anisotropy barriers of 47.

Heterometallic Octanuclear Ni Ln (Ln = Y, Gd, Tb, Dy, Ho, Er) Complexes Containing Ni Ln O Distorted Cubane Motifs: Synthesis, Structure, and Magnetic Properties.

The reaction of 2-methoxy-6-[{2-(2-hydroxyethylamino)ethylimino}methyl] phenol (LH) with lanthanide metal salts followed by the addition of nickel acetate allowed isolation of a family of octanuclear complexes, [NiLn(μ-OH)(μ-OH)(μ-OOCCH)(LH)]·(OH)·HO. Single crystal X-ray diffraction studies of these complexes reveal that their central metallic core consists of two tetranuclear [NiLnO] cubane subunits fused together by acetate and hydroxide bridges. The magnetic study of these complexes reveals a ferromagnetic interaction between the Ln and the Ni center.

Radial to axillary nerve transfer.

Axillary nerve injury is common after brachial plexus injuries, particularly with shoulder luxation. Nerve grafting is the traditional procedure for postganglionic injuries. Nerve transfer is emerging as a viable option particularly in late referrals.

Improving the SMM and luminescence properties of lanthanide complexes with LnO cores in the presence of Zn: an emissive ZnDy single ion magnet.

Mononuclear complexes of stoichiometry [Ln(HL)(HO)(NO)](NO) (Ln = Tb, 1; Dy, 2, Er, 3), which crystallise with different solvates, and the heterotrinuclear compound [ZnDy(L)(NO)(OH)] (4) can be obtained with the same HL compartmental ligand. The single X-ray crystal structure of the mononuclear complexes shows a LnO core with a muffin-like disposition while the geometry of the DyO core in 4 seems to be closer to spherical capped square antiprism. The analysis of the magnetic properties of all the complexes demonstrates that the mononuclear lanthanide compounds do not show slow relaxation of the magnetization, even when the samples are diluted with a diamagnetic matrix and subjected to a dc applied field of 1000 Oe.

Heterometallic Zn Ln Ensembles Containing (μ -CO ) Ligand and Triangular Disposition of Ln ions: Analysis of Single-Molecule Toroic (SMT) and Single-Molecule Magnet (SMM) Behavior.

Two new heterometallic Zn Ln (Ln =Dy, Tb) complexes, with a double triangular topology of the metal ions, have been assembled from the polytopic Mannich base ligand 6,6'-{[2-(dimethylamino)ethylazanediyl]bis(methylene)}bis(2-methoxy-4-methylphenol) (H L) with the aid of an in situ generated carbonate ligand from atmospheric CO fixation. Theoretical calculations indicate axial ground states for the Ln ions in these complexes, with their local magnetic moments being almost coplanar and tangential to the Ln atoms that define the equilateral triangle. Therefore, they can be considered as single-molecule toroics (SMTs) with almost zero total magnetic moment.