Publications by authors named "Juan-Luis Onieva-Zafra"
Biomedicines
January 2022
Article Synopsis
- Targeted therapy in metastatic melanoma can significantly shrink tumors and improve long-term survival by triggering immune responses through antigen release.
- Blood samples from 19 patients undergoing this treatment were analyzed to identify gene expression changes, showing that certain genes were activated while others were inhibited during treatment.
- Despite poorer clinical characteristics in patients compared to earlier studies, the radiological response rates were comparable, indicating the potential for gene expression patterns to serve as biomarkers for immune responses and guide future combination therapies.
