GCN5 regulates ZBTB16 through acetylation, mediates osteogenic differentiation, and affects orthodontic tooth movement.

In the process of orthodontic tooth movement (OTM), periodontal ligament fibroblasts (PDLFs) must undergo osteogenic differentiation. OTM increased the expression of Zinc finger and BTB domain-containing 16 (ZBTB16), which is implicated in osteogenic differentiation. Our goal was to investigate the mechanism of PDLF osteogenic differentiation mediated by ZBTB16.

[Effect of anatomical parameters of maxillary sinus on the outcomes of transcrestal sinus lift].

Objective: To investigate the effect of three anatomical parameters (maxillary sinus width, maxillary sinus angle, and residual bone height) on the outcomes of transcrestal sinus lift with simultaneous implant placement.

Methods: A total of 60 maxillary sinuses in 42 patients were included in this study. All patients were treated with transcrestal sinus lift procedure associated with simultaneous implant placement using a composite graft material of autogenous bone and Bio-Oss.

miR-221-3p and miR-222-3p downregulation promoted osteogenic differentiation of bone marrow mesenchyme stem cells through IGF-1/ERK pathway under high glucose condition.

Objective: This study aims to investigate the roles of miR-221-3p and miR-222-3p in the regulation of osteogenic differentiation of bone marrow mesenchyme stem cells (BMSCs) under high glucose condition.

Materials And Methods: The expreesions of miR-221-3p, miR-222-3p and insulin-like growth factor 1 (IGF-1) were detected by qRT-PCR. The protein levels of osteoblast-related proteins (Osterix, Runx-2 and Osteopontin) were detected by western blot.

[Finite element contact stress analysis of simulating teeth with wedge shaped defects in the cervical region].

Objective: To study the distribution of stress of simulating teeth with wedge shaped defects in the cervical region.

Methods: The models of anisotropic enamel of the mandibular first premolar and the opposite maxillary first premolar crown were created. A defect was introduced into the model of mandibular premolar in the buccal cervical region along the enamelo-dentinal junction (DEJ).

[Structural characteristics of laser-welded cast pure titanium joints by different gap distance].

Objective: To measure the microstructure of laser-welded cast pure titanium by different gap distance.

Methods: Forty specimens were sectioned and welded at four gaps (0.00 mm, 0.

[Effects of laser welding on bond of porcelain fused cast pure titanium].

Objective: To investigate the influence of the laser welding on bond of porcelain fused to cast pure titanium.

Methods: Twenty cast titanium plates were divided into two groups: laser welded group and control group. The low-fusing porcelain was fused to the laser welded cast pure titanium plates at fusion zone.