Prediction model of hepatocellular carcinoma development in chronic hepatitis B virus infection in a Spanish cohort.

Introduction And Objectives: To identify risk factors associated with the development of hepatocellular carcinoma (HCC) in an unselected cohort of patients with chronic B virus infection (CHB) in Spain. A predictive model was developed to assess the risk of HCC.

Material And Methods: A prospective open-cohort study recruited 446 unselected patients with chronic hepatitis B infection from two hospitals in Málaga (Spain).

Predictive factors of risk of hepatocellular carcinoma in chronic hepatitis C.

Objective: To identify risk factors associated with the development of HCC and develop a score to identify high risk subgroups.

Methods: We conducted a follow-up study, with biannual ultrasound and alpha-fetoprotein screening, in an unselected cohort of patients with chronic hepatitis C referred for evaluation from the primary care.

Results: 863 patients with chronic hepatitis C were followed for an average of 82 months.