Oxidative Stress in ICU Patients: ROS as Mortality Long-Term Predictor.

Lipid peroxidation, protein oxidation, and mutations in mitochondrial DNA generate reactive oxygen species (ROS) that are involved in cell death and inflammatory response syndrome. ROS can also act as a signal in the intracellular pathways involved in normal cell growth and homeostasis, as well as in response to metabolic adaptations, autophagy, immunity, differentiation and cell aging, the latter of which is an important characteristic in acute and chronic pathologies. Thus, the measurement of ROS levels of critically ill patients, upon admission, enables a prediction not only of the severity of the inflammatory response, but also of its subsequent potential outcome.

Improving the competency of medical students in clinical breast examination through a standardized simulation and multimedia-based curriculum.

Purpose: Clinical breast examination (CBE) is an important step in the assessment of patients with breast-related complaints. We developed a standardized simulation and multimedia-based (SSMBI) curriculum using current evidenced-based recommendations. This study aimed to determine if SSMBI training resulted in better performance (examination scores and detection of abnormal findings) than the traditional teaching method.

Relationship between Psychological Capital and Psychological Well-Being of Direct Support Staff of Specialist Autism Services. The Mediator Role of Burnout.

This study investigates the specific role of burnout as a mediator in the relationship between psychological capital and psychological well-being (PWB) in direct support staff of specialist autism services. A time lagged design with three data-collection points was conducted to survey 56 professionals (direct support staff) who work at a Spanish center specialized in autism. Participants completed measures of psychological capital, burnout and PWB.

Insufficiently studied factors related to burnout in nursing: Results from an e-Delphi study.

Objective: This study aimed to identify potentially important factors in explaining burnout in nursing that have been insufficiently studied or ignored.

Methods: A three-round Delphi study via e-mail correspondence was conducted, with a group of 40 European experts. The e-Delphi questionnaire consisted of 52 factors identified from a literature review.