Background/aim: Head and neck cancer (HNC) is the sixth most common type of cancer worldwide. While it is widely accepted that human papillomavirus (HPV) infection is a crucial risk factor for the development of this type of cancer, there is still a lack of support from large-scale studies. This article addresses this gap by comprehensively analyzing the causal relationship between HPV infection and head and neck cancer using Mendelian randomization methods.
View Article and Find Full Text PDFEnviron Sci Technol
February 2025
Polymeric membranes serve as vital separation materials in diverse energy and environmental applications. A comprehensive understanding of three-dimensional (3D) structures of membranes is critical to performance evaluation and future design. Such quantitative 3D structural information is beyond the limit of most employed conventional two-dimentional characterization techniques such as scanning electron microscopy.
View Article and Find Full Text PDFChronic high-altitude hypoxia (CHH) induces irreversible abnormalities in various organisms. Emerging evidence indicates that CHH markedly suppresses bone mass and bone strength. Targeting senescent cells and the consequent senescence-associated secretory phenotype (SASP) with senolytics is a recently developed novel therapy for multiple age-related diseases.
View Article and Find Full Text PDFAmong environment contaminants, Pb and Po have gained significant research attention due to their radioactive toxicity. Moss, with its exceptional adsorption capability for these radionuclides, serves as an indicator for environmental Pb and Po pollution. The paper reviews a total of 138 articles, summarizing the common methods and analytical results of Pb and Po research in moss.
View Article and Find Full Text PDFScope: Cellular senescence (CS) is closely related to tissue ageing including bone ageing. CS and the senescence-associated secretory phenotype (SASP) have emerged as critical pathogenesis elements of senile osteoporosis. This study aims to investigate the effect of lycopene on senile osteoporosis.
View Article and Find Full Text PDFIncreasing crop yields to ensure food security while also reducing agriculture's environmental impacts to ensure green sustainable development are great challenges for global agriculture. Plastic film, widely used to improve crop yield, also creates plastic film residue pollution and greenhouse gas emissions that restricts the development of sustainable agriculture. So, one of those challenges is to reduce plastic film use while also ensuring food security, and thus promote green and sustainable development.
View Article and Find Full Text PDFRadiation therapy (RT) is a crucial part of many treatment plans for cancer patients. However, major undesired side effects are associated with this treatment, including impaired bone remodeling and bone loss. Irradiation induces bone loss due to promoted osteoclastic bone resorption and reduced osteoblastic bone formation.
View Article and Find Full Text PDFNitrocellulose (NC) is widely used in both military and civilian fields. Because of its high chemical sensitivity and low decomposition temperature, NC is prone to spontaneous combustion. Due to the dangerous properties of NC, it is often dissolved in other organic solvents, then stored and transported in the form of a solution.
View Article and Find Full Text PDFAn increased fracture risk is often observed in cancer patients undergoing radiotherapy (RT), particularly at sites within the field of radiation. Therefore, the development of appropriate therapeutic options to prevent RT-induced bone loss is urgently needed. A soluble form of the BMP receptor type 1A fusion protein (mBMPR1A-mFc) serves as an antagonist to endogenous BMPR1A.
View Article and Find Full Text PDFGlucocorticoid-induced osteoporosis (GIOP) is a frequent complication of systemic glucocorticoid (GC) therapy, is the most common form of secondary osteoporosis, and is associated with skeletal fragility and increased fracture risk. A soluble form of BMP receptor type 1A fusion protein (mBMPR1A-mFc) acts as an antagonist to endogenous BMPR1A and could increase bone mass in both ovariectomized and ovary-intact mice, but its effects in GIOP mice remained unclear. The aim of this study was to evaluate the effects of mBMPR1A-mFc on the skeleton in experimental models of GIOP.
View Article and Find Full Text PDFGuang Pu Xue Yu Guang Pu Fen Xi
April 2016
This paper proposes the analyzing method of adopting wavelength dispersive X-ray fluorescence spectrometry to measure the content of Cu and Zn in PM2.5. PTFE membrane is used to prepare standard samples and atmospheric particulate samples; a research into sample cup’s structure,using polypropylene film of 6.
View Article and Find Full Text PDFGuang Pu Xue Yu Guang Pu Fen Xi
April 2016
X-ray tube is the most commonly used equipment in X-ray fluorescence spectrum analysis as excitation source whose primary spectrum has become a major source of the background of X-ray fluorescence spectrum. Background subtraction should go before further analysis of this spectrum. The accuracy of the estimation of the background directly affect the results of subsequent processing steps.
View Article and Find Full Text PDFGuang Pu Xue Yu Guang Pu Fen Xi
July 2015
N, Na, Mg, Al, Si, P, S, Cl, K, Ca, Ti, Cr, Mn, Fe, Ni, Cu, Zn, Br, Rb, Sr, Ba and Pb in herb tea were determined by X-ray fluorescence spectrometry with pressed powder pellets. The measuring conditions of target elements were investigated, including how to select its analytical line. In addition to Ba and Pb using L line, Kalpha line was selected for the rest.
View Article and Find Full Text PDFThe present paper discusses the influence of matrix effect on measurement results when portable energy dispersive X-ray fluorescence analyzer is used for the determination of Ni in soil. Based on the scattered X-ray intensity of WL(alpha) emitted from the X-ray tube on the sample, a correction method was proposed, and it combines with the correction of absorption element, which can effectively overcome the matrix effect. The correlation coefficient of the content prediction model based on this method is 0.
View Article and Find Full Text PDFGuang Pu Xue Yu Guang Pu Fen Xi
February 2012
Raman spectroscopy was used to study the influence of ultraviolet-A(UV-A) radiation on collagen I. The Raman spectra of collagen I and that after 90 min UV-A radiation were reported. The results proved that irradiation with 90 min UV-A caused the change in the structures of collagen I.
View Article and Find Full Text PDFUltraviolet B (UVB) has been widely used in dermatological phototherapy. Narrowband UVB (NB-UVB), with a peak at 311 nm, is considered to be more effective than broadband UVB (BB-UVB). However, the safety of NB-UVB is controversial.
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