Publications by authors named "Juan Rosales"

Tropical forest restoration presents a potential lifeline to mitigate climate change and biodiversity crises in the Anthropocene. Yet, the extent to which human interventions, such as tree planting, accelerate the recovery of mature functioning ecosystems or redirect successional trajectories toward novel states remains uncertain due to a lack of long-term experiments. In 2004-2006, we established three 0.

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Objectives: The aim of this study is to analyse the diagnostic value of positron emission tomography (PET) in patients with giant cell arteritis (GCA) despite glucocorticoid (GC) therapy before PET acquisition.

Methods: Consecutive patients with strongly suspected GCA according to 2022 EULAR/ACR criteria were included. The physician diagnosis of GCA after 6 months of follow-up was the gold standard.

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Article Synopsis
  • A 63-year-old man, with a history of prostate cancer, underwent a 68 Ga-PSMA-11 PET/CT scan because his PSA levels indicated a recurrence of the disease after a year of being treated.
  • The scan revealed multiple areas of uptake in the upper body, accompanied by a physical exam that showed numerous ruby-red dome-shaped papules, which were identified as cutaneous hemangiomas.
  • These cherry hemangiomas are common benign skin growths, highlighting the importance of careful interpretation of scan results to differentiate between cancerous and non-cancerous conditions.
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Objectives: Epigenetically modified fibroblasts contribute to chronicity in inflammatory diseases. Reasons for the relapsing character of large vessel vasculitis (LVV) remain obscure, including the role of fibroblasts, in part due to limited access to biopsies of involved tissue.68Ga FAPI-46 (FAPI)-PET/CT detects activated fibroblasts in vivo.

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A 76-year-old man undergoing hormone therapy for prostate cancer was referred for 68 Ga-PSMA-11-PET (PSMA PET) due to persistently detectable PSA level. No PSMA-positive tumor lesions were detected, so a delayed phase imaging was performed, which revealed focal PSMA uptake in the right seminal vesicle together with contrast accumulation on excretory phase contrast-enhanced CT. These findings were finally determined to be secondary to urinary reflux as a consequence of a prostatic enucleation he had undergone 5 months earlier following an episode of acute urinary retention.

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Multiple myeloma (MM) is the second most common haematological malignancy and remains incurable despite therapeutic advances. F-FDG (FDG) PET/CT is a relevant tool MM for staging and it is the reference imaging technique for treatment evaluation. However, it has limitations, and investigation of other PET tracers is required.

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Objetive: To evaluate the enterohepatic circulation of 75-Selenium turoselecolic acid (Se-SeHCAT) during the first 3 h and its correlation with the abdominal retention at the 7th day (AR), as contribution to the clinical study of biliar acid malabsorption (BAM).

Materials And Methods: 38 patients with chronic diarrhea were retrospectively studied. Acquisition protocol included static abdominal images at 1st, 2nd and 3rd hour and the 7th day after oral administration of the radiopharmaceutical.

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Objetive: To evaluate the enterohepatic circulation of 75-Selenium turoselecolic acid (Se-SeHCAT) during the first 3 hours and its correlation with the abdominal retention at the 7 day (AR), as contribution to the clinical study of biliar acid malabsorption (BAM).

Materials And Methods: 38 patients with chronic diarrhea were retrospectively studied. Acquisition protocol included static abdominal images at 1, 2 and 3 hour and the 7 day after oral administration of the radiopharmaceutical.

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Purpose: To investigate within phantoms the minimum CT dose allowed for accurate attenuation correction of PET data and to quantify the effective dose reduction when a CT for this purpose is incorporated in the clinical setting.

Methods: The NEMA image quality phantom was scanned within a large parallelepiped container. Twenty-one different CT images were acquired to correct attenuation of PET raw data.

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Objectives: To analyze the feasibility of DWI-MRI and ADC to evaluate treatment response in patients with multiple myeloma (MM). To correlate the variations of ADC and SUVmax in F-FDG PET-CT.

Methods: 27 patients with MM that had a whole-body MRI and F-FDG PET-CT performed at baseline and after treatment were retrospectively recruited between February 2018 and May 2020.

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Bovine herpesvirus (BoHV) types 1 and 5 are two closely related alpha-herpesviruses of cattle with neuroinvasive potential. BoHV-5 causes non-suppurative meningoencephalitis in calve whereas encephalitis caused by BoHV-1 has been occasionally reported. As an initial step to understand the biology of both BoHV types in neural cells, undifferentiated SH-SY5Y human neuroblastoma cells were infected with BoHV-1 strains Cooper and Los Angeles (LA), BoHV-5 strain 97/613 and A663, a BoHV-5/BoHV-1 natural recombinant.

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Both dispersal- and niche-based factors can impose major barriers on tree establishment. Our understanding of how these factors interact to determine recruitment rates is based primarily on findings from mature tropical forests, despite the fact that a majority of tropical forests are now secondary. Consequently, factors influencing seed limitation and the seed-to-seedling transition (STS) in disturbed landscapes, and how those factors shift during succession, are not well understood.

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Bovine herpesvirus types 1 (BoHV-1) and 5 (BoHV-5) are two closely related alphaherpesviruses. BoHV-1 causes several syndromes in cattle, including respiratory disease and sporadic cases of encephalitis, whereas BoHV-5 is responsible for meningoencephalitis in calves. Although both viruses are neurotropic, they differ in their neuropathogenic potential.

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Bovine alphaherpesvirus types 1 (BoHV-1) and 5 (BoHV-5) are closely related alphaherpesviruses. BoHV-5 causes non-suppurative meningoencephalitis in calves. BoHV-1 is associated with several syndromes and, occasionally, can cause encephalitis.

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Background And Aims: Different Volatile Organic Compounds (VOCs) obtained from several human fluids (volatolome) has been reported as potential biomarkers for a great variety of diseases including cancer. At present, volatolomic profile data of the female genital area is scarce.

Methods: To identify the VOCs related to the female genitourinary area of healthy and Cervical Cancer (CC)-affected women used a pad, as a non-invasive tool for sample gathering was necessary.

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Statement Of Problem: The impact of conventional prosthetic treatment on both the objective and subjective assessments of mastication as well as on well-being is unclear.

Purpose: The purpose of this clinical study was to compare the impact on oral health-related quality of life and masticatory function in participants treated with conventional dental prostheses.

Material And Methods: A total of 72 patients requiring prosthetic rehabilitation were enrolled by referral from the Faculty of Dentistry at the University of Granada, Spain.

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American tegumentary leishmaniasis (ATL) is a disease transmitted to humans by the female sandflies of the genus Lutzomyia. Several factors are involved in the disease transmission cycle. In this work only rainfall and deforestation were considered to assess the variability in the incidence of ATL.

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The adulteration and traceability of olive oils are serious problems in the olive oil industry. In this work, a method based on laser-induced breakdown spectroscopy (LIBS) and neural networks (NNs) has been developed and applied to the identification, quality control, traceability, and adulteration detection of extra virgin olive oils. Instant identification of the samples is achieved using a spectral library, which was obtained by analysis of representative samples using a single laser pulse and treatment by NNs.

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Objective: We compared perioperative and short-term outcomes of renal laparoscopic partial nephrectomy (LPN) and laparoscopic cryoablation (LCA) in patients with small (<3.5 cm) renal cortical neoplasms.

Methods: A retrospective analysis from our prospectively established database was performed.

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Objectives: To present our experience with patients who elected active surveillance for renal cortical neoplasms (RCNs) with ≥5 years of follow-up. Few data are available regarding the long-term natural history of RCNs during surveillance.

Methods: We retrospectively reviewed our urologic oncology database and identified 44 patients with 51 RCNs who had received active surveillance for >5 years of follow-up.

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Introduction: The endoscopic deployment and extraction of endoluminal stents, such as ureteral stents, is commonplace in contemporary medical management of many diseases. In a hemorrhagic environment, endoscopic identification of a stent can be challenging. To date, no study has evaluated the optimal color for endoscopic stent identification.

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Objectives: We evaluated the comfort level of our laparoscopy team during and after laparoscopic renal surgery, with or without the use of gel footpads.

Methods: Between September 2008 and April 2009 we prospectively randomized 100 consecutive laparoscopic renal procedures to examine whether the use of a foot gel pad altered the surgical team's comfort level. A questionnaire was used to measure the discomfort in 18 different subjects before and during surgery, and one day postoperatively.

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Purpose: We retrospectively evaluated our single center experience with patients with renal cortical neoplasms who elected active surveillance.

Materials And Methods: We retrospectively evaluated our urological oncology database between January 1993 and January 2009, identifying a total of 223 renal cortical neoplasms in 212 patients that were initially managed by active surveillance. We described patient and tumor characteristics, and assessed the differences between patients who remained on AS and those who underwent delayed intervention or progressed with metastasis.

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Objective: To compare the effectiveness of intramuscular (IM) olanzapine and typical IM antipsychotics in naturalistically treated acutely agitated patients with schizophrenia or acute mania.

Methods: During the acute phase, 2011 inpatients (including emergency settings) were assessed at 2, 24 and 72 h, and 7 days following initial injection and on oral antipsychotic transition. Mean change in agitation was assessed via Positive and Negative Symptom Scale-Excited Component (PANSS-EC) and Clinical Global Impressions-Severity (CGI-S) scores.

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