Publications by authors named "Juan Pedro Russo"
Article Synopsis
- The study investigates if patients sensitized to methylisothiazolinone (MI) also react to other isothiazolinone derivatives, specifically octylisothiazolinone (OIT) and benzisothiazolinone (BIT).
- Out of 116 patients tested, 13% were sensitized to MI, with a subset showing positive reactions to OIT upon re-testing.
- The findings suggest that strong sensitization to MI may lead to immunologic cross-reactivity with OIT, but less so with BIT.
Introduction: Severe atopic dermatitis (AD) treatment is an unmet need, given the limited efficacy and safety of classical systemic treatments (CSTs). Dupilumab is a monoclonal antibody that blocks the signaling of the interleukins that mediate the inflammatory response involved in AD.
Methods: the clinical response of a group of patients from Argentina with severe AD and insufficient response and/or toxicity to CSTs who were treated with dupilumab before commercial availability was analyzed.
Unlabelled: Case 1: A 17-year-old male rural worker from Bolivia living in La Plata (Argentina) for the past year had a lesion on the flexor side of his right forearm (6 x 4 cm). The lesion was formed by several confluent nodular areas, wine-red in color, some fistulized, with hemopurulent drainage. The area was hot and painless (Figure 1).
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